A bond swap algorithm for simulating dynamically crosslinked polymers.

Materials incorporating covalent adaptive networks (CAN), e.g., vitrimers, have received significant scientific attention due to their distinctive attributes of self-healing and stimuli-responsive properties.

Entropy-Driven Thermo-gelling Vitrimer.

Thermo-gelling polymers have been envisioned as promising smart biomaterials but limited by their weak mechanical and thermodynamic stabilities. Here, we propose a new thermo-gelling vitrimer, which remains at a liquid state because of the addition of protector molecules preventing the crosslinking, and with increasing temperature, an entropy-driven crosslinking occurs to induce the sol-gel transition. Moreover, we find that the activation barrier in the metathesis reaction of vitrimers plays an important role, and experimentally, one can use catalysts to tune the activation barrier to drive the vitrimer to form an equilibrium gel at high temperature, which is not subject to any thermodynamic instability.

Robust perfluorophenylboronic acid-catalyzed stereoselective synthesis of 2,3-unsaturated -, -, - and -linked glycosides.

A convenient protocol was developed for the synthesis of 2,3-unsaturated , - and -linked glycosides (enosides) using 20 mol % perflurophenylboronic acid catalyst via Ferrier rearrangement. Using this protocol, D-glucals and L-rhamnals reacted with various , - and -nucleophiles to give a wide range of glycosides in up to 98% yields with mainly α-anomeric selectivity. The perflurophenylboronic acid successfully catalyzed a wide range of substrates (both glucals and nucleophiles) under very mild reaction conditions.