Chemical profiling and biological activities of the roots of .

is one of the best-known endemic saponin bearing food plants of Central Asia. However, the plant's secondary metabolites remain unmapped. The current study aimed to chemical profile of the metabolite in the plant roots by an untargeted UHPLC-ESI-MS, together with the isolation of the major compounds followed by a 2D NMR and HR-MS for identification and evaluation of the antioxidant and enzyme inhibitory activity of the extracts.

UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of (Caryophyllaceae).

A crude methanol extract of the roots of (syn. ) (collected from the Tashkent region of Uzbekistan) was chemically characterised by UHPLC-ESI-QTOF-MS/MS analysis. The results indicate the presence of six major bisdesmosidic saponins derived from gypsogenin, gypsogenic and quillaic acids, including five compounds reported for the first time for this species.

GC-MS Chemical Profiling, Biological Investigation of Three Species Growing in Uzbekistan.

is a potentially valuable aromatic herb that has been used since ancient times. The present work studied the chemical profile of three species essential oils (EO): , and , as well as assessing their antioxidant and enzyme inhibitory activities. A total of 144 compounds were detected by GC-MS analysis, representing 91.

Ecdysteroids as Potent Enzyme Inhibitors and Verification of Their Activity Using In Vitro and In Silico Docking Studies.

Ecdysteroids represent arthropods' steroidal hormones, and they exist in about 5-6% of plant species. In this study, the enzyme inhibitory activity of 20 ecdysteroids was assessed for the first time via determining their inhibition versus acetylcholinesterase, butyrylcholinesterase, tyrosinase, as well as α-amylase enzymes. Furthermore, 20-Hydroxyecdysone-2,3,22-tri--acetate () showed the highest inhibition of acetylcholinesterase and butyrylcholinesterase with values of 5.

GC-MS Based Identification of the Volatile Components of Six Species from Uzbekistan and Their Biological Activity.

The compositions of volatile components in the aerial parts of six species, namely (), (), (), (), () and (), were investigated using gas chromatograph-mass spectrometry (GC-MS) analysis. Ninety-seven metabolites were identified, accounting for 73.28, 87.