Polydopamine-modified interface improves the immobilization of natural bioactive-dye onto textile and enhances antifungal activity.

Dermatomycosis, such as candidiasis and mycosis among others, has emerged recently as the most frequent fungal infection worldwide. This disease is due to the skin's exposure to microorganisms that are able to pass through skin barrier defects. Therefore, textiles in direct contact with skin can serve as a source of contamination and fungus spread.

Effect of electrolyte composition and deposition current for Fe/Fe-P electroformed bilayers for biodegradable metallic medical applications.

With its proven biocompatibility and excellent mechanical properties, iron is an excellent source material for clinical cardiac and vascular applications. However, its relatively low degradation rate limits its use for the healing and remodeling of diseased blood vessels. To address these issues, a multi-purpose fabrication process to develop a bilayer alloy composed of electroformed iron (E-Fe) and iron-phosphorus (Fe-P) was employed.

A comparison of adsorbed and grafted fibronectin coatings under static and dynamic conditions.

Coatings for medical devices are expected to improve their surface biocompatibility mainly by being bioactive, i.e. stimulating healing-oriented interactions with living cells, tissues and organs.

The use of multiple pseudo-physiological solutions to simulate the degradation behavior of pure iron as a metallic resorbable implant: a surface-characterization study.

Understanding the interactions of a pure iron surface with biological elements, such as ions and proteins in an aqueous medium, is essential for an accurate in vitro assessment of corrosion patterns. In fact, the synergy of chlorides, carbonates, phosphates and complex organic molecules present in the body environment is a key factor affecting both in vivo and in vitro degradation of materials, especially iron and its alloys. The aim of this work was the assessment of degradation patterns of pure iron in 5 commercial pseudo-physiological solutions by a thorough study of degraded surface chemistry and morphology.

Enhancing the functionality of cotton fabric by physical and chemical pre-treatments: A comparative study.

Recently, antimicrobial and decontaminating textiles, such as cotton a natural carbohydrate polymer, are generating more attention. Plant materials used for natural dyes are expected to impart biofunctional properties and high added valued functional textiles. In the current study, surface modification of cotton to maximize the dye amount on the surface has been investigated.

In vitro degradation behavior of Fe-20 Mn-1.2C alloy in three different pseudo-physiological solutions.

High manganese austenitic steels such as Fe-20Mn-1.2C alloys are among the most promising candidates for biodegradable stents applications due to their high strength, high ductility and their chemical composition. In the current work, 14 day static in-vitro tests were performed in controlled atmosphere to assess the degradation behavior in three common pseudo-physiological solutions, i.

Influence of cross-rolling on the micro-texture and biodegradation of pure iron as biodegradable material for medical implants.

Iron-based biodegradable metals have been shown to present high potential in cardiac, vascular, orthopaedic and dental in adults, as well as paediatric, applications. These require suitable mechanical properties, adequate biocompatibility while guaranteeing a low toxicity of degradation products. For example, in cardiac applications, stents need to be made by homogeneous and isotropic materials in order to prevent sudden failures which would impair the deployment site.

Effect of grain sizes on mechanical properties and biodegradation behavior of pure iron for cardiovascular stent application.

Pure iron has been demonstrated as a potential candidate for biodegradable metal stents due to its appropriate biocompatibility, suitable mechanical properties and uniform biodegradation behavior. The competing parameters that control the safety and the performance of BMS include proper strength-ductility combination, biocompatibility along with matching rate of corrosion with healing rate of arteries. Being a micrometre-scale biomedical device, the mentioned variables have been found to be governed by the average grain size of the bulk material.

On the long term antibacterial features of silver-doped diamondlike carbon coatings deposited via a hybrid plasma process.

Environmental surfaces are increasingly recognized as important sources of transmission of hospital-acquired infections. The use of antibacterial surface coatings may constitute an effective solution to reduce the spread of contamination in healthcare settings, provided that they exhibit sufficient stability and a long-term antibacterial effect. In this study, silver-incorporated diamondlike carbon films (Ag-DLC) were prepared in a continuous, single-step plasma process using a hybrid, inductively coupled plasma reactor combined with a very-low-frequency sputtering setup.

Mutant huntingtin is present in neuronal grafts in Huntington disease patients.

Objective: Huntington disease (HD) is caused by a genetically encoded pathological protein (mutant huntingtin [mHtt]), which is thought to exert its effects in a cell-autonomous manner. Here, we tested the hypothesis that mHtt is capable of spreading within cerebral tissue by examining genetically unrelated fetal neural allografts within the brains of patients with advancing HD.

Methods: The presence of mHtt aggregates within the grafted tissue was confirmed using 3 different types of microscopy (bright-field, fluorescence, and electron), 2 additional techniques consisting of Western immunoblotting and infrared spectroscopy, and 4 distinct antibodies targeting different epitopes of mHtt aggregates.