Publications by authors named "Ranmei Wei"
In the contemporary era of drug discovery, herbal treatments have demonstrated an unparalleled ability to produce anticancer drugs. An important part of the therapy of cancer is the use of plants and their by-products via analogues, which alter the tumor microenvironment and several signaling pathways. The objective of the current investigation was to conclude the rate at which the herbal medications quercetin (QT) and sulforaphane (SFN) repressed the growth of breast carcinoma cells in MDA-MB-231 by preventing the ERK/MAPK signaling systems.
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- Axillary lymph node dissection is commonly performed on breast cancer patients with a positive sentinel lymph node, but it may be unnecessary for some with negative non-sentinel lymph nodes.
- This study analyzed 456 early stage breast cancer patients to identify risk factors for non-sentinel lymph node metastasis among those with a positive sentinel lymph node.
- Key findings indicated that factors like tumor size over 2 cm, having 3 or more positive sentinel lymph nodes, a ratio of positive sentinel lymph nodes over 50%, and the presence of macrometastases are significant predictors of non-sentinel lymph node metastasis, potentially guiding surgical decisions to reduce overtreatment.