Publications by authors named "Ranmalee Amarasekara"
Article Synopsis
- Clostridioides difficile infection (CDI) causes significant diarrhea and is commonly treated with antibiotics, although these often fail or recur; understanding the microbiome in CDI patients is crucial.
- This study examined stool samples from 358 patients (180 CDI-negative and 178 CDI-positive) to analyze how clinical factors relate to their gut bacteria profiles.
- Findings revealed that the severity of CDI affected the microbiome, with significant differences in bacterial diversity linked to higher white blood cell counts and creatinine levels in infected patients.
Background: 125 million women are pregnant each year in malaria endemic areas and are, therefore, at risk of Malaria in Pregnancy (MiP). MiP is the direct consequence of Plasmodium infection during pregnancy. The sequestration of Plasmodium falciparum parasites in the placenta adversely affects fetal development and impacts newborn birth weight.
View Article and Find Full Text PDFBackground: A major challenge in dengue management in resource limited settings is the confirmation of diagnosis. Clinical features of dengue often overlap with other infections and molecular diagnostic tools are not readily accessible to clinicians at hospitals. In addition, the prediction of plasma leakage in dengue is also difficult.
View Article and Find Full Text PDFAim: This study was aimed at detecting, identifying, quantifying and comparing the bacteria present in the placental tissues of women with pre-eclampsia with that of normotensive pregnant women.
Material And Methods: Placental tissue samples were collected from 55 primiparous women with pre-eclampsia (cases) and 55 matched primiparous normotensive pregnant women (controls) at the time of delivery by cesarean section. Genotyping was carried out in two stages.