Publications by authors named "Ranjitha Rajendran"
Article Synopsis
- Trophoblast mitochondria are crucial for placental energy metabolism and can be affected by hyperandrogenism, which is linked to pregnancy complications like pre-eclampsia and gestational diabetes.
- The study evaluates mitochondrial function in four trophoblast cell lines to identify the best model for examining the effects of androgens on mitochondrial performance.
- Results indicate that ACH-3P cells have the highest respiratory capacity and show altered mitochondrial activity with testosterone exposure, supporting the connection between hyperandrogenism and mitochondrial dysfunction in the placenta.
An 8-year-old girl with recently diagnosed Systemic Lupus Erythematosus (SLE) (class 4 lupus nephritis with autoimmune hemolytic anemia) presented to the pediatric nephrology clinic with polyuria, tiredness and cramps; laboratory investigations revealed refractory hypokalemia, hypomagnesemia, metabolic alkalosis, hypocalciuria and hyperchloriuria. There was no history of diuretic administration. These features were consistent with the Gitelman syndrome.
View Article and Find Full Text PDF