Publications by authors named "Ranjit Sah"
Antimicrobial resistance (AMR) is an emerging global threat. It increases mortality and morbidity rates and places a heavy burden on healthcare systems. Healthcare professionals can address the increasing issue of AMR by advocating responsible antibiotic use and supporting the development of new medications.
View Article and Find Full Text PDFBackground: Endemic in more than 20 countries, Chagas disease affects 6.3 million people worldwide, leading to 28,000 new infections and 7700 deaths each year. Previous meta-analyses on antiparasitic treatment need updates to encompass recent studies and to assess key clinically meaningful endpoints.
View Article and Find Full Text PDFBackground And Aims: Artificial Intelligence (AI) beginning to integrate in healthcare, is ushering in a transformative era, impacting diagnostics, altering personalized treatment, and significantly improving operational efficiency. The study aims to describe AI in healthcare, including important technologies like robotics, machine learning (ML), deep learning (DL), and natural language processing (NLP), and to investigate how these technologies are used in patient interaction, predictive analytics, and remote monitoring. The goal of this review is to present a thorough analysis of AI's effects on healthcare while providing stakeholders with a road map for navigating this changing environment.
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- The study focused on analyzing multidrug-resistant (MDR) isolates for their ability to form biofilms and the presence of associated genes at a hospital in Nepal.
- A significant majority of the isolates were found to be strong biofilm producers, with 195 out of 200 being MDR and 192 capable of biofilm formation.
- Cinnamaldehyde was the most effective compound in inhibiting biofilm formation, with essential oils and Tween 80 also showing high efficacy, providing insights for potential treatment options against these resistant strains.
Monkeypox, a zoonotic virus in the , has drawn global attention for its impact on public health. In the current Mpox outbreak, a novel clade, Ib, has emerged as a significant and potentially fatal threat. This review examines the dynamics of MPXV transmission, person-to-person spread, and infection mechanisms, highlighting key risk factors.
View Article and Find Full Text PDFMpox, formerly known as monkeypox, has re-emerged as a significant global health concern, particularly during the widespread outbreak of 2022. As an orthopoxvirus related to the eradicated smallpox virus, mpox has been primarily managed with smallpox vaccines and treatments, including the antiviral agent Tecovirimat. This systematic review aims to evaluate the effectiveness and safety of Tecovirimat in treating mpox, focusing on its use during the 2022 outbreak, especially among high-risk populations, including men who have sex with men and people living with HIV.
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- * The article reviews the historical spread, transmission, and various determinants (epidemiological, social, and climatic) affecting yellow fever outbreaks over time.
- * Despite the widespread distribution of yellow fever vectors, outbreaks are largely confined to endemic areas, influenced by complex interactions between the virus, host, and vector immune responses.
Article Synopsis
- The outbreak of Monkeypox (Mpox), especially the clade 1b variant, has become a significant global health issue, particularly in Africa, which is experiencing ongoing epidemics that require urgent attention and study.
- This research analyzes data from the most affected African countries, using time series techniques to predict Mpox trends and assess the growth in new cases from August 2023 to August 2024.
- Results indicate a worrying upward trend in Mpox cases, with projections suggesting nearly 6,923 cumulative cases in about 65 weeks, highlighting the need for ongoing monitoring and tailored public health responses to manage the outbreak effectively.
Pharmacotherapy has deinstitutionalized the patients with psychotic disorder. This has led to the transfer of the caregiving burden from hospitals to family members of the patients. This study aimed to assess the caregivers' burden and the factors associated with it objectively.
View Article and Find Full Text PDFThe recent global resurgence of Mpox (formerly monkeypox), primarily transmitted via close contact and respiratory droplets, highlights a significant shift in its epidemiology, particularly among men who have sex with men (MSM). This resurgence underscores the need for robust public health responses and improved surveillance. This comprehensive review of current literature focuses on recent outbreaks, virology, and available treatments.
View Article and Find Full Text PDFBackground: Toxoplasmosis is a chronic protozoan parasitic infection that affects nearly one-third of the global population. During the COVID-19 pandemic, cases were observed in patients with COVID-19 and toxoplasmosis. Therefore, this systematic review and meta-analysis aimed to determine the frequency of Toxoplasma gondii exposure in patients with COVID-19.
View Article and Find Full Text PDFBackground: Although the recent literature indicates that mpox (monkeypox) primarily affects men, there are also multiple reports in women. Estimates of the sex distribution of mpox patients and patterns will enable a better understanding of the ongoing mpox outbreak.
Methods: In this systematic review and meta-analysis, seven databases were searched for studies published in English up to January 4, 2023.