Publications by authors named "Ranjan K Sharma"

Ruptured sinus of Valsalva aneurysm (RSOV) is an uncommon cause of high output heart failure. RSOV most commonly opens into the right ventricle followed by the right atrium and non-coronary cusp involvement is relatively uncommon. Infective endocarditis (IE) is a rare cause of RSOV.

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Background: Early changes in cardiac function due to ischemia may be detected by global longitudinal peak systolic strain (GLS). Till date, no Indian data exist regarding role of GLS in stable ischemic heart disease (SIHD) and data showing correlation of GLS and SYNTAX score (SS) is meager in world literature. Our aim was to ascertain the role of GLS in SIHD.

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Article Synopsis
  • The study aimed to evaluate the prevalence of high central aortic pressure (CAP) in Indian patients suffering from uncontrolled essential hypertension despite taking single antihypertensive medications.
  • Researchers enrolled patients aged 30-70 with high brachial blood pressure, finding that a significant 84.3% had high central systolic blood pressure at baseline, indicating a widespread issue.
  • Results revealed that measurement of CAP alongside brachial blood pressure could be crucial for managing hypertension effectively, highlighting the varying effectiveness of different antihypertensive medications.
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•Here, we are presenting a very rare case of coarctation of abdominal aorta where a transcatheter closure by a vascular plug of the feeding collateral to a large aneurysm has been done. To the best of our knowledge, this mode of therapy has never been described in persons with coarctation of abdominal aorta.•Aneurysms in patients with an abdominal coarctation are not well recognized.

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Background: Left ventricular diastolic dysfunction (LVDD) is observed frequently in advanced COPD and it appears unrelated to the co-presence of its common risk factors as hypertension, diabetes, ischemic heart disease, etc. The patho-physiology of this association is yet unclear. We postulated that ischemia not apparent in the routine clinical evaluation could be the cause of such LVDD.

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