Publications by authors named "Rania S Ismail"
Background: A central role for apolipoprotein E (APOE) has been suggested in modulating processes of neurodegeneration.
Objective: To study the association between serum APOE levels, APOE gene polymorphisms, and Parkinson's disease (PD).
Material And Methods: Fifty-five patients with PD and 30 healthy subjects were enrolled.
Background: Although the pathogenesis of idiopathic intracranial hypertension (IIH) is still poorly understood, the contribution of inflammatory mechanisms has been proposed in its pathophysiology.
Objective: This study aimed to measure serum tumor necrosis factor-α (TNF-α) levels in patients with IIH and to examine its relationship with clinical and ophthalmological parameters and cerebrospinal fluid (CSF) opening pressure.
Subjects And Methods: Thirty-six IIH patients and 30 healthy subjects were enrolled in the study.
Background: Anecdotal reports have proposed that diet might influence the occurrence of seizures.
Objectives: Our objectives were to assess nutritional status in a sample of patients with epilepsy and to investigate the impact of nutrition on epilepsy control.
Patients And Methods: One hundred and fifty patients with epilepsy participated in the study.
Background: Studies have just started delineating the role of Toll-like receptors (TLRs) in the pathogenesis of multiple sclerosis (MS).
Objectives: To investigate the expression of TLR-2 and TLR-4 on peripheral blood neutrophils and lymphocytes in Egyptian patients with MS, and to examine the role of TLR-2 and TLR-4 expression as a candidate biomarker for MS diagnosis.
Methods: A total of 84 patients with newly diagnosed MS and 68 healthy controls were included in this study.
Memory, cognition and visuospatial aspects of temporal lobe epilepsy (TLE) have not been fully analyzed yet. From among the huge growing population of circulating apoproteins analyzed in TLE, apolipoprotein E (APOE) was discovered; however, its role in TLE has not been fully elucidated yet. This study was designed to investigate the relation between the serum level of APOE and cognition in TLE patients.
View Article and Find Full Text PDFEffect of transcranial direct current stimulation on cognitive function in stroke patients.
Egypt J Neurol Psychiatr Neurosurg
November 2018
Background: Cognitive impairment after stroke is common and can cause disability with major impacts on quality of life and independence. Transcranial direct current stimulation may represent a promising tool for reconstitution of cognitive functions in stroke patients.
Objectives: This study aimed to investigate the effect of transcranial direct current stimulation on cognitive functions in stroke patients.
Evaluation of bone health among epileptic patients using biochemical markers and DEXA scan: an Egyptian study.
Egypt J Neurol Psychiatr Neurosurg
April 2018
Background: An association between antiepileptic drugs, low bone mineral density (BMD), fractures, and abnormalities in bone metabolism has been suggested for a longer period, although conclusive evidence has not been reported.
Methods: Thirty epileptic patients and 30 matched healthy subjects participated in the study. Measurements of serum levels of calcium, phosphorus, vitamin D, parathormone, and alkaline phosphatase were done for included subjects.
Background: Hyperhomocysteinemia, vitamin B12 and folate deficiency have been linked to cognitive dysfunction in multiple sclerosis (MS) patients.
Objective: This study aimed to investigate the relation of serum homocysteine (Hcy), vitamin B12 and folate to cognitive functions in MS patients.
Subjects And Methods: Forty-five MS patients and twenty matched healthy controls were included.