Background: Malignant ovarian germ cell tumors represent small percentage of malignant ovarian neoplasms but they affect significantly young age group.
Aim Of The Study: To investigate the immunohistochemical expression of p16 tumor suppressor protein in malignant ovarian germ cell tumors.
Materials And Methods: Twenty-two malignant ovarian germ cell tumors (five dysgerminoma, eight immature teratoma, and nine yolk sac tumors), twenty mature cystic teratoma tumors and twenty normal ovarian tissue were immunohistochemically stained with p16 monoclonal antibody.