Enteral administration of a simulated amniotic fluid in preventing feeding intolerance in very low birthweight neonates: A randomized controlled trial.

Objectives: Feeding intolerance (FI) is a common finding in preterm neonates. Enteral administration of different forms of amniotic fluid (AF) has been tried for treating FI in high-risk neonates. Simulated amniotic fluid (SAF) is a solution with a similar electrolyte composition to human AF.

Gut priming with bovine colostrum and T regulatory cells in preterm neonates: a randomized controlled trial.

Background: Necrotizing enterocolitis (NEC) and neonatal sepsis are still considered major problems, especially in formula-fed preterm neonates. This study aimed to investigate the effect of bovine colostrum on T regulatory cells, NEC, and late-onset sepsis in preterm neonates ≤34 weeks.

Methods: This prospective double-blind randomized controlled trial was conducted on 80 preterm infants who were randomly assigned to either the bovine colostrum group (n = 32) or control group (n = 48).

High serum APRIL levels strongly correlate with disease severity in pediatric atopic eczema.

Background: Expression of the tumor necrosis factor (TNF) family member APRIL (a proliferation-inducing ligand) is low in normal tissues but is elevated in various autoimmune diseases.

Objectives: This study explored serum APRIL in children with atopic eczema (AE) during flare and quiescence.

Methods: A case-control study including 50 patients with AE and 40 control subjects was conducted.

Gentamicin extended interval regimen and ototoxicity in neonates.

Objectives: To assess the extended interval regimen gentamicin associated ototoxicity in neonatal intensive care unit using hearing tests.

Methods: Two hundred and twenty neonates admitted to neonatal intensive care were assessed; 110 neonates who had received gentamicin and 110 neonates who had not received gentamicin served as control group. Gentamicin group were further subdivided according to the duration of treatment into 50 neonates who had received gentamicin for 5 days or less and 60 neonates who had received gentamicin for more than 5 days.

Effect of caffeine on preterm infants' cerebral cortical activity: an observational study.

Objective: Our first aim was to investigate the effects of caffeine on preterm infants' respiratory functions and brain cortical activity (conventional and amplitude-integrated electroencephalography (cEEG and aEEG)). Secondary aim was to study its long-term effects on respiratory system and electroencephalographic maturation by 36 weeks post-menstrual age.

Methods: Prospective observational study on 33 consecutively admitted preterm infants less than 34-weeks-gestation.