Publications by authors named "Rania Gaspo"

Objective: The Pharma Collaboration for Transparent Medical Information (phactMI™) benchmarking survey was conducted to evaluate the use of technology and websites associated with the medical information (MI) departments of 27 biopharmaceutical companies in the United States.

Methods: The e-survey was administered to phactMI™ members between December 2017 and February 2018 and included closed and open-ended questions with 7 distinct categories: existence of a MI website, content type available following a search query, website functions, search engine optimization (SEO), website traffic, internal communications/analytics, and additional technology capabilities.

Results: Survey findings noted that 20 companies own a MI-specific website through which MI services are provided to healthcare providers (HCPs).

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Objectives: This study of 23 US-based biopharmaceutical medical information (MI) websites was conducted to assess usability and identify best practices and areas of potential improvement.

Methods: In this systematic review, websites were evaluated from June 22-November 1, 2016, and awarded points based on content, functionality, and navigation (maximum score of 42). Low-, mid-, and high-range usability scores were ≤13, 14-27, ≥28, respectively.

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Introduction: Fluorescence in situ hybridization (FISH) is currently the standard for diagnosing anaplastic lymphoma kinase (ALK)-rearranged (ALK+) lung cancers for ALK inhibitor therapies. ALK immunohistochemistry (IHC) may serve as a screening and alternative diagnostic method. The Canadian ALK (CALK) study was initiated to implement a multicenter optimization and standardization of laboratory developed ALK IHC and FISH tests across 14 hospitals.

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Objective: To evaluate the severity of glaucoma at presentation and the relationship to referral source and presenting symptoms.

Design: Prospective, multicentre, cross-sectional, study.

Participants: Patients newly diagnosed with ocular hypertension (OH) or open-angle glaucoma (OAG).

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Article Synopsis
  • The study aimed to analyze ocular variables, risk factors, and severity levels in patients newly diagnosed with ocular hypertension (OH) and open-angle glaucoma (OAG).
  • A total of 405 subjects participated, with 292 having OAG and 113 having OH; among those with OAG, 51.7% had early-stage, 27.1% moderate, and 20.9% advanced disease.
  • The research found that older age increased the risk of developing OAG but interestingly indicated that smoking might lower that risk compared to OH, with many patients presenting with moderate to advanced stages at diagnosis.
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Aromatase inhibitors (AIs) have been shown to reduce the risk of breast cancer recurrence and are widely used today as adjuvant therapy in women with early stage endocrine-responsive breast cancer. Aromatase inhibitors may be prescribed as initial hormonal therapy, sequentially following 2-3 years of tamoxifen, or as extended adjuvant therapy (following 5 years of tamoxifen). Aromatase inhibitors are generally well tolerated; however, certain side effects, particularly arthralgia/musculoskeletal symptoms and gynecologic effects, may result in poor adherence to treatment.

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Purpose: Acromegaly is a rarely diagnosed condition with potentially serious complications including accelerated heart disease and reduced survival. After a mean interval of nearly 9 years from onset of disease, a significant proportion of patients are diagnosed with invasive adenomas precluding complete surgical resection. Furthermore, strict normalization of the growth hormone (GH) target insulin-like growth factor I (IGF-I) cannot always be achieved by adjunctive medical therapy with somatostatin analogues.

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