Publications by authors named "Rania Gaber Aly"
Article Synopsis
- Pleuropulmonary Blastoma (PPB) is a rare and aggressive tumor affecting the lungs or pleura, classified into three types: cystic (type I), mixed (type II), and solid (type III), with type I having the best outlook.
- There is currently no standard treatment due to its rarity, and the importance of early identification in differential diagnosis of cystic lung lesions is emphasized through a review of four cases.
- A retrospective study from 2015 to 2020 showed diverse clinical presentations in four pediatric patients diagnosed with PPB, with all cases missed prior to surgery, highlighting the need for increased awareness and vigilance in diagnosis.
Whether chronic inflammation in the genital tract induced by obesity shares in spermatogenic dysfunction is not clearly known. We aimed to study the effect of high fat diet (HFD) on spermatogenesis, seminal oxidative stress (malondialdehyde (MDA)) and inflammatory markers (high mobility group box 1 (HMGB1), nucleotide-binding oligomerization domain, leucine rich repeat and pyrin-3 domain containing (NLRP3)) in the rat testes and the role of zinc on testicular dysfunction and chronic inflammation in high fat diet (HFD) fed rat testes. This parallel group comparative experimental study included 36 male wistar rats divided into 3 groups: group A (fed on normal control diet); group B (fed on high fat diet (HFD) only); and group C (fed on HFD with zinc supplementation 3.
View Article and Find Full Text PDFBackground: Several treatment modalities are available for the treatment of vitiligo due to the lack of a uniformly effective therapy. Topical latanoprost 0.005% is an effective topical treatment.
View Article and Find Full Text PDFBackground: Spermidine is a natural biologically active substance that has widespread influences on the body.
Objective: This study aims to enhance our understanding of the potential effect of spermidine on long non-coding RNA MALAT1 and explore the underlying mechanism in the rotenone-induced rat model of Parkinson's disease.
Methods: Rats were sacrificed after locomotor behavioral testing.
Influence of narrow-band ultraviolet B therapy on sirtuin 1 expression in lesional skin of patients with chronic plaque psoriasis: Relation to clinical improvement and interferon-γ expression.
Photodermatol Photoimmunol Photomed
November 2022
Background: Reduced sirtuin 1 (Sirt1) expression in psoriasis was previously reported, and its activation was associated with disease improvement. Narrow-band ultraviolet B (NB-UVB) downregulates several pro-inflammatory cytokines such as interferon-γ (IFN-γ) and influences keratinocyte differentiation in psoriasis.
Objectives: The aim of this study was to study the in vivo influence NB-UVB treatment on Sirt1 expression in psoriatic skin in relation to disease improvement and IFN-γ expression.