Chromosomal Variations and Clinical Features of Acute Lymphoblastic Leukemia in the North Indian Population: A Cross-Sectional Study.

Background: The key prognostic markers in acute lymphoblastic leukemia (ALL) include age, leukocyte count upon diagnosis, immunophenotype, and chromosomal abnormalities. Furthermore, there was a correlation between cytogenetic anomalies and specific immunologic phenotypes of ALL, which in turn had varied outcomes. The objective of this study was to examine the occurrence of cytogenetic abnormalities in individuals diagnosed with acute lymphoblastic leukemia.

Reduced and oxidized rice straw biochar for hexavalent chromium adsorption: Revisiting the mechanism of adsorption.

Surface oxygen functional groups of biochar were tuned by oxidation and reduction of biochar for establishing Cr(VI) adsorption mechanism. Oxygen functional groups (OFGs) on the surface of leached rice straw biochar (LBC4-6) obtained from pyrolysis at 400, 500 and 600 °C, were oxidized to furnish OBC4-6 using modified Hummer's method. Reduced biochar RBC4-6 were obtained by esterification and NaBH/I reduction of oxidized biochar (OBC4-6).

Discovery of potent inhibitors for M enzyme of SARS-COV2 by multi-stage in-silico screening of Alkannin/shikonin.

Novel coronavirus disease, a serious challenge for the healthcare system, has diverted all the researchers toward the exploration of potential targets, compounds or vaccines for the management of this disease. M enzyme was found to be crucial for replication of this virus which makes this enzyme an attractive drug target for SARS-CoV-2. Diverse pharmacological profile of Alkannin/shikonin (A/S) derivatives build up curiosity to study their antiviral profile.

Histological changes at the commissure of the lip on approaching from its cutaneous to the mucosa region in males.

Introduction: The morphology of the epithelium of the oral lips comprised keratinized external epithelium (anteriorly) and nonkeratinized or sometimes parakeratinized mucous membrane epithelium (posteriorly). Knowledge of morphometry of the lip lining helps in deciding the best site for choosing graft for its better uptake during several dermal grafting procedures following trauma or tumor excision following craniofacial cancers or cosmetic procedures.

Materials And Methods: Ten human male cadavers were procured at the Department of Anatomy King George's Medical University, Lucknow, Uttar Pradesh.

Guidewire Mishap: An Avoidable Iatrogenic Complication.

Unlabelled: Central vein catheterization is a commonly used technique in indoor patients. It is mainly used for venous access, allowing administration of drugs, fluids, chemotherapy, blood components. Central vein catheterisation may lead to many complication which includes bleeding, perforation of veins and hematoma formation, thrombosis, infections, bleeding, needle stick injury, air embolism, kinking or looping of the wire tip, breakage of a guidewire, etc.

Re-evaluation of superficial fascia of anterior abdominal wall: a computed tomographic study.

Purpose: Understanding the topographic anatomy of the membranous layer of superficial fascia of anterior abdominal wall may help in explaining the body contour deformities and provide the anatomic basis for surgical corrections. Existing controversies in the presence and extent of membranous layer of the superficial fascia of anterior abdominal wall among anatomists and misinterpretation of its anatomical description by clinicians provoked us to re-evaluate the superficial fascia of anterior abdominal wall.

Method: Fifty CT scans of abdominal region of either sex were studied to see the vertical and horizontal extent of membranous layer.

Anomalous formation of external jugular vein and its clinical implication.

Introduction: The superficial veins, especially the external jugular vein (EJV), are increasingly being utilized for cannulation to conduct diagnostic procedures or intravenous therapies. EJV is also used in microsurgical procedures,used as a recipient for the free flaps.

Materials And Methods: During routine dissection a variation was observed in the formation of EJV unilaterally on the left side.

Incidence of osseous interclinoid bars in Indian population.

Purpose: Parasellar interclinoid bars are significant in surgical management while dealing with the vascular, neoplastic or traumatic lesions of the central skull base and can also compress the surrounding structures giving rise to various clinical symptoms. The literature cites several case reports but systematic study of these bars has not been done. Therefore this study was carried out to see the incidence of osseous interclinoid bars in Indian population.