Publications by authors named "Rangarajan K"

 The aim of this study was to assess efficacy of large language models (LLMs) for converting free-text computed tomography (CT) scan reports of head and neck cancer (HNCa) patients into a structured format using a predefined template.  A retrospective study was conducted using 150 CT reports of HNCa patients. A comprehensive structured reporting template for HNCa CT scans was developed, and the Generative Pre-trained Transformer 4 (GPT-4) was initially used to convert 50 CT reports into a structured format using this template.

View Article and Find Full Text PDF

 The aim of this study was to compare the performance of four publicly available large language models (LLMs)-GPT-4o, GPT-4, Gemini, and Claude Opus-in translating radiology reports into simple Hindi.  In this retrospective study, 100 computed tomography (CT) scan report impressions were gathered from a tertiary care cancer center. Reference translations of these impressions into simple Hindi were done by a bilingual radiology staff in consultation with a radiologist.

View Article and Find Full Text PDF

Objectives: The interpretation of mammograms requires many years of training and experience. Currently, training in mammography, like the rest of diagnostic radiology, is through institutional libraries, books, and experience accumulated over time. We explore whether artificial Intelligence (AI)-generated images can help in simulation education and result in measurable improvement in performance of residents in training.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates using advanced 3D U-Net architectures, along with Inception and ResNet modules, to enhance the detection of lung nodules through deep learning in order to develop a Computer-Aided Diagnosis (CAD) system.
  • Four different 3D U-Net models were trained using a dataset from AIIMS Delhi, incorporating data augmentation techniques and a hybrid loss function for optimization, while performance was evaluated using metrics like Dice and Jaccard coefficients on a set of CT scans.
  • The ensemble method combining multiple models showed the best results, achieving a higher average Dice score and reduced false positives compared to individual models, indicating it could significantly improve lung nodule detection in clinical applications.
View Article and Find Full Text PDF

 Although abundant literature is currently available on the use of deep learning for breast cancer detection in mammography, the quality of such literature is widely variable.  To evaluate published literature on breast cancer detection in mammography for reproducibility and to ascertain best practices for model design.  The PubMed and Scopus databases were searched to identify records that described the use of deep learning to detect lesions or classify images into cancer or noncancer.

View Article and Find Full Text PDF

Data Privacy has increasingly become a matter of concern in the era of large public digital respositories of data. This is particularly true in healthcare where data can be misused if traced back to patients, and brings with itself a myriad of possibilities. Bring custodians of data, as well as being at the helm of disigning studies and products that can potentially benefit products, healthcare professionals often find themselves unsure about ethical and legal constraints that undelie data sharing.

View Article and Find Full Text PDF

The presence of lung metastases in patients with primary malignancies is an important criterion for treatment management and prognostication. Computed tomography (CT) of the chest is the preferred method to detect lung metastasis. However, CT has limited efficacy in differentiating metastatic nodules from benign nodules (e.

View Article and Find Full Text PDF

Purpose: The proposed work aims to develop an algorithm to precisely segment the lung parenchyma in thoracic CT scans. To achieve this goal, the proposed technique utilized a combination of deep learning and traditional image processing algorithms. The initial step utilized a trained convolutional neural network (CNN) to generate preliminary lung masks, followed by the proposed post-processing algorithm for lung boundary correction.

View Article and Find Full Text PDF

We encountered a giant dermatofibrosarcoma protuberans (DFSP) of the neck and chest wall which presented a challenge in terms of perioperative analgesia management. In recent years, erector spinae plane (ESP) block has emerged as an effective and safe analgesia technique for various surgical procedures as well as for chronic neuropathic pain without any untoward complications. A continuous lower cervical ESP block can be used successfully as an effective analgesic technique for extensive DFSP surgery involving the neck and chest wall area.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to enhance deep learning techniques for detecting isodense or obscure masses in dense breast tissue by incorporating core radiology principles into model development.
  • Using a multi-centre approach, the researchers trained and validated the deep learning model on both diagnostic and screening mammography datasets, which included thousands of images and confirmed cases of cancer.
  • Results showed improved sensitivity in detecting malignancies, especially in patients with dense breasts and isodense cancers, suggesting that integrating traditional radiology knowledge into deep learning can significantly boost cancer detection performance.
View Article and Find Full Text PDF

Aims: The conventional Seldinger and trocar techniques of percutaneous nephrostomy (PCN) have inherent limitations in infants and younger children. We studied the role of a novel coaxial technique of PCN in children under the age of 5 years in comparison to the conventional techniques.

Materials And Methods: This was a single-center feasibility trial based on 24 consecutive patients ( = 24 kidneys) under the age of 5 years, conducted over 12 months, substratified into Group I ( = 10): PCN with conventional Seldinger ( = 2) and trocar ( = 8) techniques and Group II ( = 14): PCN with proposed coaxial technique.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzes 41 patients with central nervous system (CNS) metastases from epithelial ovarian cancer (EOC) between 2010 and 2020, highlighting that only 3.98% of patients developed these metastases.
  • The median age of patients was 48 years, and the majority had advanced stage EOC, with a median time of 27 months from EOC diagnosis to CNS metastasis.
  • Key findings indicate that patients with isolated CNS metastases and receiving aggressive treatment had better outcomes, with median progression-free survival of 12 months and overall survival of 33 months; lower serum CA-125 levels were associated with improved survival.
View Article and Find Full Text PDF

Unlabelled: Governments are recognizing anticompetitive concerns and market distortions associated with the rise of e-commerce platforms. Thus, policies are being crafted to level the playing field between large platform operators and small platform sellers. In addition, policies mitigating barriers to internationalization associated with using e-commerce platforms are also being developed.

View Article and Find Full Text PDF

Background: Performing ultrasound during the current pandemic time is quite challenging. To reduce the chances of cross-infection and keep healthcare workers safe, a robotic ultrasound system was developed, which can be controlled remotely. It will also pave way for broadening the reach of ultrasound in remote distant rural areas as well.

View Article and Find Full Text PDF

Introduction The COVID-19 pandemic has been a major public health threat for the past three years. The RNA virus has been constantly evolving, changing the manifestations and progression of the disease. Some factors which impact the progression to severe COVID-19 or mortality include comorbidities such as diabetes mellitus, hypertension, and obesity.

View Article and Find Full Text PDF

While detection of malignancies on mammography has received a boost with the use of Convolutional Neural Networks (CNN), detection of cancers of very small size remains challenging. This is however clinically significant as the purpose of mammography is early detection of cancer, making it imperative to pick them up when they are still very small. Mammography has the highest spatial resolution (image sizes as high as 3328 × 4096 pixels) out of all imaging modalities, a requirement that stems from the need to detect fine features of the smallest cancers on screening.

View Article and Find Full Text PDF

With the rapid integration of artificial intelligence into medical practice, there has been an exponential increase in the number of scientific papers and industry players offering models designed for various tasks. Understanding these, however, is difficult for a radiologist in practice, given the core mathematical principles and complicated terminology involved. This review aims to elucidate the core mathematical concepts of both machine learning and deep learning models, explaining the various steps and common terminology in common layman language.

View Article and Find Full Text PDF

Introduction: The current gold standard treatment for breast cancer liver metastases (BCLM) is systemic chemotherapy and/or hormonal therapy. Nonetheless, greater consideration has been given to local therapeutic strategies in recent years. We sought to compare survival outcomes for available systemic and local treatments for BCLM, specifically surgical resection and radiofrequency ablation.

View Article and Find Full Text PDF