Characterization of oscillation modes in levitated droplets using image and non-image based techniques.

The dynamics of levitated liquid droplets can be used to measure their thermophysical properties by correlating the frequencies at which normal modes of oscillation most strongly resonate when subject to an external oscillatory force. In two preliminary works, it was shown via electrostatic levitation and processing of various metals and alloys that (1) the resonance of the first principal mode of oscillation (mode n = 2) can be used to accurately measure surface tension and (2) that so-called "higher-order resonance" of n = 3 is observable at a predictable frequency. It was also shown, in the context of future space-based experimentation on the Electrostatic Levitation Furnace (ELF), a setup on the International Space Station (ISS) operated by Japan Aerospace Exploration Agency (JAXA), that while the shadow array method in which droplet behavior is visualized would be challenging to identify the n = 3 resonance, the normal mode n = 4 was predicted to be more easily identifiable.

Benchmarking surface tension measurement method using two oscillation modes in levitated liquid metals.

The Faraday forcing method in levitated liquid droplets has recently been introduced as a method for measuring surface tension using resonance. By subjecting an electrostatically levitated liquid metal droplet to a continuous, oscillatory, electric field, at a frequency nearing that of the droplet's first principal mode of oscillation (known as mode 2), the method was previously shown to determine surface tension of materials that would be particularly difficult to process by other means, e.g.

Faraday forcing of high-temperature levitated liquid metal drops for the measurement of surface tension.

In this work, a method for the measurement of surface tension using continuous periodic forcing is presented. To reduce gravitational effects, samples are electrostatically levitated prior to forcing. The method, called Faraday forcing, is particularly well suited for fluids that require high temperature measurements such as liquid metals where conventional surface tension measurement methods are not possible.

Novel phenylalanine derived diamides as Factor XIa inhibitors.

The synthesis, structural activity relationships (SAR), and selectivity profile of a potent series of phenylalanine diamide FXIa inhibitors will be discussed. Exploration of P1 prime and P2 prime groups led to the discovery of compounds with high FXIa affinity, good potency in our clotting assay (aPPT), and high selectivity against a panel of relevant serine proteases as exemplified by compound 21. Compound 21 demonstrated good in vivo efficacy (EC50=2.

Can an adverse density difference across a surface be stabilized by heating from above?

We investigate the possibility of stabilizing a Rayleigh-Taylor experiment by imposing a small upward temperature gradient. We find that if the two fluids have equal thermal conductivities nothing can be accomplished. If either thermal conductivity is much greater than the other, the small gradient is always stabilizing.

Mixing generated by Faraday instability between miscible liquids.

The mixing between two miscible liquids subject to vertical vibrations is studied by way of experiments and a two-dimensional numerical model. The experimental setup consisted of a rectangular cell in which the lighter fluid was placed above the denser one. The diffuse interface was then visualized by a high-speed camera.

Onset of Rayleigh-Marangoni convection in a cylindrical annulus heated from below.

The onset of Rayleigh-Marangoni convection in a vertical annulus heated from below is investigated using linear stability analysis. The results of the present study also show the pattern transitions as a function of scaled gap width and aspect ratio. It is concluded that Marangoni convection can change the fluid pattern in an otherwise pure Rayleigh problem.