The high frequency properties of brain tissue.

Computer modeling is becoming increasingly important in the realm of brain biomechanics and injury. New computer simulations range from modeling of brain surgery, a low frequency, high strain event, to predicting injury as a result of an impact to the head, a high frequency event with varying strain magnitudes. This range of modeling efforts requires characterization of the tissue over as wide a frequency and strain range as possible.

Problems of cervical cancer screening programmes.

The feasibility of using an age-sex register as a basis for a cervical cancer screening programme was investigated in a London practice serving both inner city and suburban populations. Only about 25% of 810 women aged 35-59 years who had not recently been screened responded to an invitation to attend a practice well woman clinic for a cervical smear. Nearly 30% of the invitations were returned ;not known at this address' and there was no reply from the remaining 45%.

A study of cancer of the breast and other sites in women after total colectomy and ileostomy for non-malignant disorders.

To assess the role in breast-cancer aetiology of oestrogenic substances apparently produced by intestinal bacteria from faecal residues associated with a high-fat diet and other absorbable and possibly carcinogenic colonic substances, cancer incidence and mortality were studied in 2425 women in the UK who had previously had total colectomy and terminal ileostomy, mostly for ulcerative colitis for Crohn's disease. The incidence of breast cancer in this group of women was no lower than would be expected, although there was a slight deficiency of deaths from this cause. These findings suggest that, at least in adult life, the colon is not involved in the aetiology of breast cancer.

Cancer in furniture workers.

A follow-up study of 5371 men who had worked in 1 or more of 9 furniture factories in Buckinghamshire for an average of 19 years up to 1968 is reported. The incidence of nasal adenocarcinoma in furniture workers taken as a whole was found to be about one hundred times that expected in the local population, and a significant relationship was found between increasing incidence of the tumour and increasing dustiness of work within the cohort. Similar comparisons with the local population produced no evidence for an increased risk of cancer of any other site in the furniture workers including bronchial cancer and malignant disease of the reticulo endothelial system.

Nasal cancer in England and Wales: an occupational survey.

A national survey of the incidence of nasal cancer in England and Wales during the period 1963-7 with special reference to occupation confirmed the well-known increases in incidence of nasal cancer in cabinet makers and wood machinists, together with the absence of any significant increase in carpenters and joiners, and the increases in boot and shoe operatives and repairers, and in nickel smelters in South Wales. The significant excesses of cases found among coalminers, furnacemen in the gas, coke, and chemical industry, and furnacemen and labourers in foundries may be associated with exposure to coal and coke dust or may be spurious. No excess of nasal cancer was found among male textile workers.

Adenocarcinoma of the nasal cavity and sinuses in England and Wales.

21-30. A survey of nasal adenocarcinoma in England and Wales (excluding the Oxford region) is described. Where possible, occupational details were obtained and the histological material on the basis of which the diagnosis had been made was reassessed.