Publications by authors named "Randy Maddalena"

The use of household cleaning products can result in exposure to potentially hazardous volatile and semi-volatile organic compounds (VOCs and SVOCs). "Green" cleaning products have become increasingly available, but there is no official "green" standard, and it is difficult for consumers to know what chemicals they may be exposed to while cleaning. We measured air concentrations of 46 VOCs and SVOCs of concern released from conventional and "green" cleaning products during both real-world household cleaning and a controlled chamber environment, with a focus on chemicals that might increase women's risk of breast cancer, including possible carcinogens, reproductive/developmental toxicants, or endocrine disruptors.

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Background: Household cleaning products may be a significant source of chemical exposures, including carcinogens and suspected endocrine disruptors.

Objectives: We characterized exposures during routine household cleaning and tested an intervention to reduce exposures to cleaning product chemicals.

Methods: The Lifting Up Communities with Interventions and Research (LUCIR) Study is a youth-led, community-based intervention project.

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"Sub-ohm" atomizers with reduced resistance can deliver more power than conventional electronic cigarettes. Typical battery outputs are 100 W or more. These devices are particularly popular among young users, and can be a significant source of volatile carbonyls in the indoor environment.

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Vaporizable cannabis concentrates (VCCs) consumed as a liquid (vaping) or a waxy solid (dabbing) are becoming increasingly popular. However, their associated emissions and impacts have not been fully described. Mixtures containing different proportions of 12 VCC terpenoids and high MW compounds were heated at 100-500 °C inside a room-sized chamber to simulate emissions.

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Article Synopsis
  • Dry anaerobic digestion (AD) of municipal solid waste, followed by composting, helps produce biogas and improves soil quality while reducing landfill methane emissions.
  • However, emissions of other greenhouse gases and pollutants during this process can still pose climate and air quality risks.
  • Research shows that composting contributes significantly to methane and other emissions, suggesting that better aeration could help mitigate these issues.
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Ozonation is a common remediation approach to eliminate odors from mold, tobacco and fire damage in buildings. Little information exists to: 1) assess its effectiveness; 2) provide guidance on operation conditions; and 3) identify potential risks associated with the presence of indoor ozone and ozonation byproducts. The goal of this study is to evaluate chemical changes in thirdhand smoke (THS) aerosols induced by high levels of ozone, in comparison with THS aerosols aged under similar conditions in the absence of ozone.

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Microalgae produce specific chemicals indicative of stress and/or death. The aim of this study was to perform non-destructive monitoring of algal culture systems, in the presence and absence of grazers, to identify potential biomarkers of incipient pond crashes. Here, we report ten volatile organic compounds (VOCs) that are robustly generated by the marine alga, , in the presence and/or absence of the marine grazer, .

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Approximately 13 million U.S. children less than 6 years old spend some time in early childhood education (ECE) facilities where they may be exposed to potentially harmful chemicals during critical periods of development.

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Infants and young children spend as much as 50h per week in child care and preschool. Although approximately 13 million children, or 65% of all U.S.

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While small- and medium-sized commercial buildings (SMCBs) make up 96% of the commercial buildings in the U.S., serving a large variety of uses, little information is available on indoor air quality (IAQ) in SMCBs.

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The effect of temperature and humidity on formaldehyde emissions from samples collected from temporary housing units (THUs) was studied. The THUs were supplied by the U.S.

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Tobacco-specific nitrosamines (TSNAs) are some of the most potent carcinogens in tobacco and cigarette smoke. Accurate quantification of these chemicals is needed to help assess public health risks. We developed and validated a specific and sensitive method to measure four TSNAs adsorbed to model surfaces and secondhand smoke (SHS) particles using gas chromatography-ion-trap tandem mass spectrometry.

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Indoor concentrations of 33 volatile organic chemicals were measured in four unoccupied temporary housing units (THUs) belonging to the U.S. Federal Emergency Management Administration (FEMA).

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Article Synopsis
  • - The study uses the global multimedia model CliMoChem and Monte Carlo simulations to predict current and future concentrations of DDT in various environments, highlighting the impact of uncertainties in data and parameters on the model's accuracy.
  • - It finds that uncertainties in DDT concentration predictions typically range from 1 to 2 orders of magnitude, with emission estimates and atmospheric degradation rates being the most significant factors affecting the model.
  • - By employing a Bayesian Monte Carlo method, the research updates model inputs using real-world DDT measurements, resulting in more accurate predictions and reduced uncertainties, thereby providing valuable insights into DDT's environmental persistence and behavior.
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The concentrations of polycyclic aromatic hydrocarbons (PAHs) were investigated in a pilot study of field wheat grain as a model indicator for environmental contamination. The edible grain would serve as a portal for human exposure. Wheat grain was initially studied since it is one of the major food crops consumed internationally by many including infants and children.

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Polycyclic aromatic hydrocarbons (PAHs) can partition from the atmosphere into agricultural crops, contributing to exposure through the dietary pathway. In this study, controlled environmental chamber experiments were conducted to investigate the transfer of PAHs from air into wheat grain, which is a major food staple. A series of PAHs ranging in size from naphthalene to pyrene were maintained at elevated gas-phase concentrations in the chamber housing mature and dry wheat grain both on the plant and with the husk removed.

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The role of terrestrial vegetation in transferring chemicals from soil and air into specific plant tissues (e.g., stems, leaves, and roots) is still not well characterized.

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Mass balance models of chemical fate and transport can be applied in ecological risk assessments for quantitative estimation of concentrations in air, water, soil, and sediment. These concentrations can, in turn, be used to estimate organism exposures and ultimately internal tissue concentrations that can be compared to mode-of-action-based critical body residues that induce toxic effects. From this comparison, risks to the exposed organism can be evaluated.

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The effectiveness of a probabilistic risk assessment (PRA) depends on the quality and relevance of the output from exposure and risk models, which, in turn, depends on the critical inputs to the assessment. These critical inputs are often in the form of probabilistic exposure factor distributions that are derived for the given risk scenario. Deriving probabilistic distributions for model inputs can be time consuming and subjective.

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Both laboratory and field studies confirm the importance of vegetation for scavenging semivolatile organic chemicals (SVOCs) from the atmosphere and a number of exposure studies have found that the dietary pathway is often a significant contributor to cumulative exposure for these chemicals. However, little information exists on the atmospheric source-to-dietary intake linkage for SVOCs. Because of higher SVOC emissions to urban regions, this linkage is particularly important for foods that are grown, distributed and consumed in or near urban regions.

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Article Synopsis
  • - The study uses a continuous flow-through exposure chamber and a mass balance model to explore how chemicals transfer between air and vegetation, specifically with mature bell pepper plants exposed to different pollutants.
  • - Key metrics evaluated include chemical partitioning (Kpa), mass transfer rates (Upa), and loss rates in both the atmosphere and plants, with specific measurements taken for pollutants like phenanthrene, anthracene, fluoranthene, and pyrene.
  • - Results showed varying partitioning values and mass transfer rates, as well as reaction half-lives in air and plants, highlighting the effectiveness of combining experimental measurements with modeling for understanding pollutant uptake in vegetation.
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