Rescue of pyrimidine-defective through metabolic complementation.

Unlabelled: Chronic infections harbor multiple pathogens where dynamic interactions between members of the polymicrobial community play a major role in determining the infection outcome. For example, in a nutrient-rich polymicrobial infection, bacteria have the potential to undergo evolutionary changes that impair their ability to synthesize essential metabolites. This adaptation may facilitate metabolic interdependencies between neighboring pathogens and lead to difficult-to-treat chronic infections.

Imaging porosity evolution of tight sandstone during spontaneous water imbibition by X-ray Micro-CT.

Water imbibition is an important process in reservoir rocks during hydraulic fracturing and water-based enhanced oil recovery operations. However, the water imbibition behavior in tight sandstones has not been fully understood due to their complex pore structure, including the presence of nano and micron-sized pores and throats, surface properties, and wide variation in mineralogy. The present study focuses on the effect of spontaneous water imbibition on the porosity evolution of a tight sandstone.