Publications by authors named "Randy Desarzant"
Article Synopsis
- Semantic dementia (SD) features progressive loss of semantic knowledge and can occur in both early and late onset, leading to potential misdiagnosis as Alzheimer's disease (AD).
- A study of 74 individuals found that 35.1% had late-onset SD (≥65 years), with no major clinical differences from early-onset SD, yet notable differences in cognitive abilities compared to AD patients.
- Identifying late-onset SD through specific cognitive tests and early personality changes can improve disease management and education, highlighting the need for better differentiation from AD.
Repetitive Behaviors in Frontotemporal Dementia: Compulsions or Impulsions?
J Neuropsychiatry Clin Neurosci
December 2019
Objective: The presence of repetitive behaviors is one of the core criteria for behavioral variant frontotemporal dementia (bvFTD). Patients with bvFTD often have perseverative, stereotyped, or compulsive-ritualistic behavior as an early aspect of their disorder. It is unclear whether such behaviors are related to compulsions, as in obsessive-compulsive disorder (OCD), or are part of the impulse disorder spectrum.
View Article and Find Full Text PDFBackground: Many patients with early-onset Alzheimer's disease (EOAD; age of onset <65 years) have non-amnestic presentations involving language (logopenic primary progressive aphasia, lvPPA), visuospatial abilities (posterior cortical atrophy, PCA), and even asymmetric symptoms consistent with corticobasal syndrome (CBS). An inferior parietal lobule variant of EOAD commonly presents with progressive difficulty with calculations.
Methods: We reviewed 276 EOAD patients for presentations with predominant acalculia.