Publications by authors named "Randi J Ryan"
Article Synopsis
- The study investigates how the type of induction therapy and high-risk viral discordance affect outcomes in kidney transplant recipients over the age of 55.
- It analyzes data from over 87,000 transplant cases between 2005 and 2022, focusing on three induction types: rabbit antithymocyte globulin (r-ATG), interleukin-2 receptor antagonist (IL-2RA), and alemtuzumab.
- Results indicate that while induction type didn't impact recipient survival, high-risk Epstein-Barr virus discordance increased mortality, and alemtuzumab was linked to a higher risk of graft loss compared to r-ATG.
The impact of bariatric surgery (BS) on kidney transplantation (KT) outcomes in patients with obesity remains controversial. We systematically searched MEDLINE, EMBASE, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials for studies reporting outcomes of KT recipients that underwent prior BS. Common/random effects meta-analyses were performed to obtain summary ratios of the postoperative outcomes.
View Article and Find Full Text PDFHerpes simplex virus 1 (HSV-1) capsids leave the nucleus by a process of envelopment and de-envelopment at the nuclear envelope (NE) that is accompanied by structural alterations of the NE. As capsids translocate across the NE, transient primary enveloped virions form in the perinuclear space. Here, we provide evidence that torsinA (TA), a ubiquitously expressed ATPase, has a role in HSV-1 nuclear egress.
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