Maternal beta-blocker dose and risk of small-for gestational-age in women with heart disease.

Introduction: Beta-blockers are prescribed for many pregnant women with heart disease, but whether there is a dose-dependent effect on fetal growth remains to be examined. We aimed to investigate if antenatal beta-blocker use and dose were associated with delivering a small-for-gestational-age infant among women with heart disease.

Material And Methods: Our cohort included women with heart disease who delivered at Oslo University Hospital between 2006 and 2015.