Publications by authors named "Randall J. Nett"

Background: Dentists can be exposed to dust and nanoparticles from teeth, dental composites, and metal alloys generated during dental procedures, and exposure to dust can cause respiratory diseases, including pulmonary fibrosis. The authors describe mortality from nonmalignant respiratory diseases (NMRDs) among dentists in the United States.

Methods: The authors submitted information on US dentists who died from 1979 through 2018 to a centralized US death records database to obtain underlying causes of death.

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Organophosphate insecticides are widely used for adult mosquito control. Although proven effective in reducing mosquito populations and limiting arbovirus transmission, public concern exists regarding potential human health effects associated with organophosphate exposure. The aim of this scoping review was to describe any reported human health conditions associated with organophosphates during their use for adult mosquito control in the United States and Canada.

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The Centers for Disease Control and Prevention's Epidemic Intelligence Service (EIS) is a fellowship in applied epidemiology for physicians, veterinarians, nurses, scientists, and other health professionals. Each EIS fellow is assigned to a position at a federal, state, or local site for 2 years of on-the-job training in outbreak investigation, epidemiologic research, surveillance system evaluation, and scientific communication. Although the original focus of the program on the control of infectious diseases remains salient, positions are available for training in other areas of public health, including occupational respiratory disease.

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Article Synopsis
  • West Nile virus (WNV) is the main cause of mosquito-borne diseases in the continental U.S., but predicting its spread is complicated due to varying factors like environment and ecology.
  • Researchers developed 10 different models, including machine learning techniques, to predict annual cases of WNV neuroinvasive disease (WNND) from 2015 to 2021 across different climate regions.
  • The study found that historical WNND cases and population density were key predictors, and while some machine learning models showed promise, none outperformed simpler models based on historical data.
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Background: Sporicidal products containing hydrogen peroxide (HP), peracetic acid (PAA), and acetic acid (AA) are used widely in multiple industries, including healthcare. Despite widespread use in healthcare, few studies have assessed associations between exposures to HP, PAA, and AA, and work-related symptoms in these settings.

Methods: In 2018, we performed a health and exposure assessment at a hospital where a sporicidal product consisting of HP, PAA, and AA, was used as the primary cleaner on hospital surfaces.

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Objective: To assess proportionate mortality from all causes for male and female US veterinarians during 1979 through 2015.

Sample: Death records for 11,620 veterinarians.

Procedures: For this proportionate mortality ratio (PMR) study, information for veterinarians who died during 1979 through 2015 was obtained from AVMA obituary and life insurance databases and submitted to a centralized database of US death records to obtain underlying causes of death.

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Background: West Nile virus (WNV) is the leading cause of mosquito-borne illness in the continental USA. WNV occurrence has high spatiotemporal variation, and current approaches to targeted control of the virus are limited, making forecasting a public health priority. However, little research has been done to compare strengths and weaknesses of WNV disease forecasting approaches on the national scale.

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Purpose: Information on incentives for COVID-19 testing is needed to understand effective practices that encourage testing uptake. We describe characteristics of those who received an incentive after performing a rapid antigen test.

Design: Cross-sectional descriptive analysis of survey data.

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Objectives: Before community transmission of COVID-19 was recognized in the United States, cruise ship passengers with high risk for exposure to SARS-CoV-2 were repatriated and quarantined. We describe cases of influenza-like illness (ILI) among responders.

Methods: We reviewed situation reports and responder illness reports to characterize ill responders, including illness onset date, symptoms, fever, diagnostic tests, potential breaches in PPE use, and return to work status.

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Article Synopsis
  • In environments where histoplasmosis is common, jobs involving contact with soil contaminated by bird or bat droppings can increase the risk of infection.
  • Occupational exposures are often linked to outbreaks of histoplasmosis, highlighting the need for awareness in certain professions.
  • The paper reviews available literature on occupationally acquired histoplasmosis, discussing its epidemiology, risk factors for workers, and prevention strategies based on a hierarchy of controls.
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Approximately 41% of adults aged 18-24 years in the United States are enrolled in a college or university (1). Wearing a face mask can reduce transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) (2), and many colleges and universities mandate mask use in public locations and outdoors when within six feet of others. Studies based on self-report have described mask use ranging from 69.

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Purpose Of Review: To examine respiratory and skin diseases that occur among workers exposed to metalworking fluids (MWFs) used during machining processes.

Recent Findings: Five cases of a severe and previously unrecognized lung disease characterized by B-cell bronchiolitis and alveolar ductitis with emphysema (BADE) were identified among workers at a machining facility that used MWFs, although MWF exposure could not be confirmed as the etiology. In the United Kingdom, MWF is now the predominant cause of occupational hypersensitivity pneumonitis (HP).

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Occupational bronchiolitis is characterized by inflammation of the small airways, and represents a heterogeneous set of lung conditions that can occur following a range of inhalation exposures related to work. The most common clinical presentation includes insidious onset of exertional dyspnea and cough. Multiple reports in recent years have drawn attention to previously unrecognized risk factors for occupational bronchiolitis following exposures in several settings.

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Roasted coffee and many coffee flavorings emit volatile organic compounds (VOCs) including diacetyl and 2,3-pentanedione. Exposures to VOCs during roasting, packaging, grinding, and flavoring coffee can negatively impact the respiratory health of workers. Inhalational exposures to diacetyl and 2,3-pentanedione can cause obliterative bronchiolitis.

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Coronavirus disease 2019 (COVID-19) is a viral respiratory illness caused by SARS-CoV-2. During January 21-July 25, 2020, in response to official requests for assistance with COVID-19 emergency public health response activities, CDC deployed 208 teams to assist 55 state, tribal, local, and territorial health departments. CDC deployment data were analyzed to summarize activities by deployed CDC teams in assisting state, tribal, local, and territorial health departments to identify and implement measures to contain SARS-CoV-2 transmission (1).

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Article Synopsis
  • * Human and environmental microbiota were analyzed, finding a significant microbial similarity between MWF and affected workers' lung tissues, especially in those from the machine shop area.
  • * The study suggests that exposure to MWF may cause harmful health effects, evidenced by increased B-cell proliferation in lab mice and the presence of harmful microbes in affected workers, indicating a public health concern.
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Objectives: Four machine manufacturing facility workers had a novel occupational lung disease of uncertain aetiology characterised by lymphocytic bronchiolitis, alveolar ductitis and emphysema (BADE). We aimed to evaluate current workers' respiratory health in relation to job category and relative exposure to endotoxin, which is aerosolised from in-use metalworking fluid.

Methods: We offered a questionnaire and spirometry at baseline and 3.

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Respiratory hazards in the coffee roasting and packaging industry can include asthmagens such as green coffee bean and other dust and alpha-diketones such as diacetyl and 2,3-pentanedione that can occur naturally from roasting coffee or artificially from addition of flavoring to coffee. We sought to describe the burden of respiratory abnormalities among workers at 17 coffee roasting and packaging facilities. We completed medical surveys at 17 coffee roasting and packaging facilities that included interviewer-administered questionnaires and pulmonary function testing.

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Background: A cluster of severe lung disease occurred at a manufacturing facility making industrial machines. We aimed to describe disease features and workplace exposures.

Methods: Clinical, functional, radiologic, and histopathologic features were characterized.

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Objective: To explore associations between demographic, occupational, and mental health characteristics and negative attitudes toward mental illness among veterinarians.

Design: Cross-sectional survey.

Sample: 9,522 veterinarians employed in the United States.

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