Widespread Necrotizing Purpura and Lucio Phenomenon as the First Diagnostic Presentation of Diffuse Nonnodular Lepromatous Leprosy.

Lucio phenomenon, or Lucio leprosy, is a rare severe lepra reaction that develops exclusively in patients with diffuse nonnodular lepromatous leprosy. It is characterized by irregular, angulated, or stellar necrotizing purpuric lesions that develop ulcerations. It mainly involves the extremities and develops as a result of massive invasion of vascular endothelial cells with lepra bacilli and secondary thrombotic vascular occlusion.

Broadband ultraviolet A in the treatment of psoriasis vulgaris: a randomized controlled trial.

Background: Broadband ultraviolet A (BB-UVA) has been successfully used in the treatment of scleroderma, a UVA1-responsive dermatosis.

Objective: To compare the efficacy of BB-UVA versus psoralen + UVA (PUVA) in psoriasis treatment and assess apoptosis as an effector mechanism.

Patients And Methods: This randomized controlled trial included 61 patients with chronic plaque psoriasis randomly divided into group I or II.

Trends of Obesity and Overweight among College Students in Oman: A cross sectional study.

Objectives: Body mass index (BMI), total body fat (TBF), and physical activity in relation to obesity and overweight prevalence among Omani students were studied.

Methods: A cross-sectional study of 202 Omani students (101 males and 101 females) from Sultan Qaboos University (SQU) was carried out. Data were collected by interview using a structured questionnaire.

Heme oxygenase-1 expression protects melanocytes from stress-induced cell death: implications for vitiligo.

To study protection of melanocytes from stress-induced cell death by heme oxygenases during depigmentation and repigmentation in vitiligo, expression of isoforms 1 and 2 was studied in cultured control and patient melanocytes and normal skin explants exposed to UV or bleaching agent 4-TBP. Similarly, expression of heme oxygenases was followed in skin from vitiligo patients before and after PUVA treatment. Single and double immunostainings were used in combination with light and confocal microscopic analysis and Western blotting.