Re-evaluation of F-FDG absorbed and effective dose in adult and pediatric phantoms using DoseCalcs Monte Carlo platform: a validation study.

Positron emission tomography (PET) using F-FDG is a well-known modality for the diagnosis of various diseases in patients of different ages, sexes, and states of health, which implies that internal radiation dosimetry is highly desired for different phantom anatomies. In this study, we validate "DoseCalcs," a new Monte Carlo platform that combines personalized internal dosimetry calculations with Monte Carlo simulations. To achieve that, we used the specific absorbed fraction (SAF) calculated by DoseCalcs and those from ICRP publication 133 to estimate the absorbed dose per injected activity (AD/IA) and effective dose per injected activity (ED/IA) for F-FDG.