In silico docking and molecular dynamics for the discovery of inhibitors of enteric methane production in ruminants - A review.

The increase in methane emissions, a major greenhouse gas, threatens human well-being and global ecosystems due to its contribution to global warming. Livestock, particularly ruminants, have been a major research topic in recent decades due to their methane production. Therefore, the objective of the current review was to comprehensively discuss the in silico techniques used to mitigate methane production from ruminants.

Investigation of the Potential of Repurposing Medium-Density Fiberboard Waste as an Adsorbent for Heavy Metal Ion Removal.

Medium-density fiberboard (MDF) waste generation has increased steadily over the past decades, and therefore, the investigation of novel methods to recycle this waste is very important. The potential of repurposing MDF waste as an adsorbent for the treatment of Cd(II), Cu(II), Pb(II), and Zn(II) ions in water was investigated using MDF offcuts. The highest adsorption potential in single-metal ion solution systems was observed for Pb(II) ions.

Successful use of neostigmine for resistant gastroparesis following distal gastrectomy: A case report.

Introduction And Importance: Although short acting acetyl cholinesterase inhibitors are used in colonic or small bowel pseudo-obstruction, their use in post-surgical gastroparesis is not clear. We demonstrate the successful use of neostigmine in a patient with resistant gastroparesis following distal gastrectomy.

Case Presentation: A 73-year-old male presented with features of gastric outflow obstruction 3 weeks following a distal gastrectomy.

- Invited Review - Factors affecting beef quality and nutrigenomics of intramuscular adipose tissue deposition.

Beef quality is characterized by marbling (marbling degree and marbling fineness), physiochemical (shear force, meat color, fat color, texture, and maturity), and sensory (tenderness, flavor, juiciness, taste, odor, and appearance) traits. This paper summarizes and addresses beef-quality characteristics and the beef-grading systems in Korea, Japan, the USA, and Australia. This paper summarizes recent research progresses on the genetic and nutritional factors that affect beef quality.

, and to Prevent Type 2 Diabetes: An Integrative Review.

Diabetes mellitus has become a global pandemic progressively rising and affecting almost every household in all world regions. Diet is a significant root cause of type II diabetes; thus, the significance of dietary interventions in preventing and managing the disease cannot be neglected. Lowering the glycemic impact of diet is an alternative way of managing type II diabetes while improving insulin sensitivity.

Partial Substitution of Corn Grain in the Diet with Beet Pulp Reveals Increased Ruminal Acetate Proportion and Circulating Insulin Levels in Korean Cattle Steers.

We investigated the effects of the partial substitution of corn grain in the diet with beet pulp on growth performance, ruminal fermentation characteristics, microbial profiles, and blood lipogenic parameters in fattening steers. Twelve Korean cattle steers (body weight, 485 ± 19.32 kg; age, 18.

Solid pseudopapillary neoplasm of the pancreas with multiple liver metastases successfully managed with staged resection.

Due to the rarity of the disease, there are no guidelines or consensus for the management of solid pseudopapillary neoplasm of the pancreas with liver metastasis. We describe a patient with solid pseudopapillary neoplasm of the pancreas with multiple liver metastases who was successfully managed with staged resection. A previously healthy 50-year-old female presented to the clinic with dull epigastric pain.

Digestive recovery of polyphenols, antioxidant activity, and anti-inflammatory activity of selected edible flowers from the family Fabaceae.

Edible flowers are regaining popularity as therapeutic agents, due to their phytochemical composition. The present study assessed the recovery of phenolics along with the antioxidant and anti-inflammatory properties of seven edible flowers of the Fabaceae family after being subjected to simulated gastrointestinal conditions and dialysis. The total phenolic content of all the flowers decreased after the gastric phase, whereas the total flavonoid content increased.

A comparative analysis of the outcome of malaria case surveillance strategies in Sri Lanka in the prevention of re-establishment phase.

Background: Sri Lanka sustained its malaria-free status by implementing, among other interventions, three core case detection strategies namely Passive Case Detection (PCD), Reactive Case Detection (RACD) and Proactive Case Detection (PACD). The outcomes of these strategies were analysed in terms of their effectiveness in detecting malaria infections for the period from 2017 to 2019.

Methods: Comparisons were made between the surveillance methods and between years, based on data obtained from the national malaria database and individual case reports of malaria patients.

Nutraceutical potential of dietary phytochemicals in edible flowers-A review.

Edible flowers have been in traditional cuisine and phytotherapy for centuries. Recently, the consumption of edible flowers has increased significantly as the phytochemicals in them are known to have numerous health benefits. Information on nutraceutical potentials and health benefits of the phytochemicals available in different varieties of edible flowers and their uses are discussed.

and Toxicity Profiles of Hexane Extract of Rhizome in Rat and Cell Line Models.

The objective of the study was to evaluate the potential toxicity of crude -hexane extract of rhizome. The acute oral toxicity was evaluated by administering a single oral dose of the extract at 0, 300, or 2000 mg/kg body weight to female Wistar rats according to modified OECD Test Guideline 423. For the cytotoxicity study, A549, HepG2, 3T3, and COS-7 cell lines were exposed to different doses of extract and cell viability was assessed adopting MTT assay followed by AO/EB staining, Hoechst staining, and comet assay with a view to compare the cellular and molecular mechanisms underlying the toxicity, if any.

Corrigendum to "Adsorptive removal of Co(II) in aqueous solutions using clearing nut seed powder" [Heliyon 6 (4) (2020) Article e03684].

[This corrects the article DOI: 10.1016/j.heliyon.

Adsorptive removal of Co(II) in aqueous solutions using clearing nut seed powder.

The present study assessed the potential use of clearing nut seed powder () as an adsorbent for the removal of Co(II) ions from aqueous solutions. Based on FTIR analysis, the adsorbent possesses hydroxyl, C-N, and C-O functional groups and SEM analysis indicated the presence of uneven porous surface structure, which is important for adsorption. Batch adsorption studies were performed to investigate the effect of contact time, initial pH, initial Co(II) concentration, adsorbent dosage, and temperature on adsorption.

Determination of macronutrient compositions in selected, frequently consumed cereals, cereal based foods, legumes and pulses prepared according to common culinary methods in Sri Lanka.

Cereal grains, legumes and pulses comprise the largest proportion in a typical South-Asian diet plate. This research is mainly focusing on determining the macronutrient composition of major cereals, legumes and pulses commonly consumed in local Sri Lankan cuisine, in their cooked form. White samba, White Basmati, Red Kekulu and Nadu rice were selected as the main rice varieties and in addition maize, and wheat, finger millet flour-based foods too were analyzed.

Influence of rumen bypass fat supplementation during early lactation in tropical crossbred dairy cattle.

The present study investigated the influence of rumen bypass fat-supplemented total mixed ration (TMR) on milk production of tropical crossbred, dairy cows. Twelve stall-fed, tropical crossbred, dairy cows were studied from calving to 15 weeks of lactation. The cows were 397.

Response surface optimization for recovery of polyphenols and carotenoids from leaves of using an ethanol-based solvent system.

Response surface methodology has been used to optimize the extraction conditions for total phenolics and carotenoids from leaves of . Solvent concentration (30%-100%), extraction temperature (30-60°C), and extraction time (30-90 min) were used as the independent variables. A second-order polynomial model produced a satisfactory fitting of the experimental data with regard to total phenolics (  = 84.

In Vitro Anti-Inflammatory Properties of Selected Green Leafy Vegetables.

The study investigated the anti-inflammatory activity of the hydro methanolic extract of six leafy vegetables, namely , , , , , and . The anti-inflammatory activity of methanolic extracts of leafy vegetables was evaluated using four in vitro-based assays: hemolysis inhibition, proteinase inhibition, protein denaturation inhibition, and lipoxygenase inhibition. Results showed that the percent inhibition of hemolysis from these leaf extracts (25⁻100 µg/mL dry weight basis (DW)) was within the range from 5.

Effect of Different Cooking Methods on Polyphenols, Carotenoids and Antioxidant Activities of Selected Edible Leaves.

This study aimed to evaluate the effect of cooking (boiling, steaming, and frying) on polyphenols, flavonoids, carotenoids and antioxidant activity of six edible leaves. The total antioxidant capacity of the fresh and cooked leaves was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and singlet oxygen scavenging assays. The results revealed that frying caused a reduction in major bioactives and antioxidant activities in all leafy vegetables tested.

Antimicrobial activity and phytochemical screening of Alpinia malaccensis (Ran-kiriya) against food-borne bacteria.

Aims: Investigation of antimicrobial activity and phytochemicals of Alpinia malaccensis (Ran-kiriya) against foodborne bacteria Staphyloccocus aureus, Listeria monocytogenes, Escherichia coli and Salmonella Typhimurium.

Methods And Results: Antibacterial activity was tested on the above four foodborne bacteria using agar disc diffusion and broth dilution assay. Alpinia malaccensis rhizome extract chemical composition was determined using gas chromatography-mass spectrometry (GCMS).

Influence of Boiling, Steaming and Frying of Selected Leafy Vegetables on the In Vitro Anti-inflammation Associated Biological Activities.

The aim of the present study was to evaluate the effect of cooking (boiling, steaming, and frying) on anti-inflammation associated properties of six popularly consumed green leafy vegetables in Sri Lanka, namely: , , , , and The anti-inflammation associated properties of methanolic extracts of cooked leaves were evaluated using four biological assays, namely, hemolysis inhibition, proteinase inhibition, protein denaturation inhibition, and lipoxygenase inhibition. Results revealed that the frying of all the tested leafy vegetables had reduced the inhibition abilities of protein denaturation, hemolysis, proteinase, and lipoxygenase activities when compared with other food preparation methods. Steaming significantly increased the protein denaturation and hemolysis inhibition in and Steaming of leaves increased inhibition activity of protein denaturation in (by 44.

Change of phenolics, carotenoids, and antioxidant capacity following simulated gastrointestinal digestion and dialysis of selected edible green leaves.

The bio-accessibility of phenolics, flavonoids, rutin, β-carotene and lutein and changes in antioxidant activities in six edible greens during simulating gastro-intestinal conditions has been investigated. It was found that the amount of dialysable phenolics, flavonoids and carotenoids which potentially available for further uptake is varying depending on the leafy type. Bioavailable phenolics after the gastric-phase, intestinal-phase and in dialysable fraction were in the ranges of 13.

The potential synergistic behaviour of inter- and intra-genus probiotic combinations in the pattern and rate of short chain fatty acids formation during fibre fermentation.

This study compared the rate of short chain fatty acid (SCFA) production by different probiotic combinations of Lactobacillus and Bifidobacterium to determine any synergistic effects. Six different fibre fractions were fermented with nine combinations of Lactobacillus rhamnosus (LR), Lactobacillus acidophilus (LA), Bifidobacterium longum (BL) and Bifidobacterium breve (BB) for 0, 6, 24 and 48 h. SCFAs were quantified by gas chromatography.

Antidiabetic Compounds in Decoction and Ready to Serve Herbal Drink.

Herbal beverages with desirable sensory attributes are an ideal way to offer consumers with phytochemicals having specific health promoting functionalities. bark decoction is used in treating diabetes mellitus in Ayurveda medicine. This work attempted to prove the presence of antidiabetic compounds in the decoction and the ready to serve (RTS) herbal drink developed using the decoction.

Effect of heat-moisture treatment on digestibility of different cultivars of sweet potato (Ipomea batatas (L.) Lam) starch.

Different heat-moisture levels were applied to native starches from different cultivars of sweet potatoes available in Sri Lanka (Wariyapola red, Wariyapola white, Pallepola variety, Malaysian variety and CARI 273) to study the digestibility level. Samples were treated with 20, 25, and 30% moisture at 85°C and 120°C for 6 h and in vitro starch digestibility was tested with porcine pancreatin enzyme. A range of 19.

Comparative analysis of nutritional quality of five different cultivars of sweet potatoes (Ipomea batatas (L) Lam) in Sri Lanka.

Nutritional attributes of flours obtained from five different cultivars of sweet potato roots commonly available in Sri Lanka showed significant differences in the tested parameters. The starch level ranged between 33% and 64% on the dry basis and the extractability from fresh tubers was governed by the quantity of starch. The crude fiber level ranged between 2.