Publications by authors named "Ranapala S Jayatilake"
J Cancer Res Ther
December 2007
Article Synopsis
- AK-2123, a hypoxic cell sensitizer, was evaluated in a randomized trial for its effectiveness when combined with radiotherapy in treating stage IIIA and IIIB uterine cervical cancer.
- A total of 333 patients participated in the study, receiving either standard radiotherapy alone or radiotherapy plus AK-2123, with promising doses administered over several weeks.
- Results showed that combining AK-2123 with radiotherapy significantly improved local tumor control and survival rates without increasing major side effects.
Radiother Oncol
January 2007
Article Synopsis
- AK-2123, a drug that enhances the effects of radiation therapy, was evaluated in a trial for its effectiveness in treating stage III and IV uterine cervical cancer alongside standard radiotherapy.
- The study included 333 patients, with half receiving only radiation therapy and the other half receiving both radiation and AK-2123 over a treatment period of around 4-5.5 weeks.
- Results showed that the combination therapy led to better local tumor control (61% vs 46%) and higher 60-month survival rates (57% vs 41%) without significantly increasing side effects.
