Novel CAD/CAM-splint-based navigation protocol enhances intraoperative maxillary position control in orthognathic surgery: a case control study.

Background: Virtual surgical planning for orthognathic surgery typically relies on two methods for intraoperative plan transfer: CAD/CAM occlusal splints and patient-specific implants (PSI). While CAD/CAM splints may offer limited accuracy, particularly in the vertical dimension, PSIs are constrained by higher costs and extended preparation times. Surgical navigation has emerged as a potential alternative, but existing protocols often involve invasive registration or lack transparent evaluation.

Differential homing of monocytes and neutrophils in the epithelial layer of HSV-1 infected cornea regulates viral dissemination and wound healing.

Purpose: To ascertain the homing of monocytes and neutrophils in the epithelium versus stroma of HSV-1 infected corneas at different stages of infection and functional significance of their anatomical location in virus-infected corneas.

Methods: The corneas of C57BL/6J mice were infected with HSV-1 McKrae. Mice were euthanized on different days post-infection.

Selective lead ion sensing via cotton pad-based NaEDTA capped AuNPs: A smartphone-assisted colorimetric method.

Herein, NaEDTA-capped AuNPs specifically designed for selective smartphone-assisted colorimetric detection are synthesized and characterized. NaEDTA-capped AuNPs was synthesized and characterized by UV-Visible spectroscopy, ATR, Raman, XRD, SEM and EDX. The calculated activation energy of the produced nanoparticles was 0.

Focused Investigation of Facial Nerve Dysfunction After Mandibular Distraction Osteogenesis for Robin Sequence.

Facial nerve dysfunction (FND) is a well-recognized but poorly documented complication of mandibular distraction osteogenesis (MDO) for Robin sequence (RS). This study aims to document the authors' experiences with FND and identify risk factors associated with this adverse event. A retrospective review of a prospectively gathered database was performed to identify patients with RS who underwent MDO at the authors' institution from March 2016 to June 2023.

The literature exploring the perspectives and experiences of racialized students in entry-level health professional education programs: a scoping review protocol.

Objective: The objective of this scoping review will be to determine the breadth of literature exploring the perspectives and experiences of racialized students in entry-level health professional education programs.

Introduction: Despite the implementation of equity, diversity, and inclusion (EDI) policies and alternative admission criteria for minority students, racialized minorities continue to be underrepresented and have the highest attrition rate in health professional education programs. Furthermore, the students who eventually work in health care settings report experiences of microaggression and prejudice.

Optimizing Pectin Yield From Burmese Grape () Peels Using Box-Behnken Design and Quality Evaluation.

Pectin, a polysaccharide, is widely used as a gelling and thickening agent in the food industry. This study undertook optimization of pectin extraction from the peels of Lour. (Burmese grape or lotkon), an abundantly grown wild fruit in Bangladesh.

Genotoxic effects of NDMA-contaminated ranitidine on Allium cepa cells and unveiling carcinogenic mechanisms via DFT and molecular dynamics simulation study.

This study investigated the potential genotoxic and carcinogenic effects of N-nitrosodimethylamine (NDMA), a hazardous compound found in ranitidine formulations that are used to treat excessive stomach acid. The study first examined the effects of NDMA-contaminated ranitidine formulation on Allium cepa root growth and mitotic activity. The results demonstrated dose-dependent decreases in both root growth and mitotic index indicating genotoxicity and cell division disruption.

A Review of Transparent Conducting Films (TCFs): Prospective ITO and AZO Deposition Methods and Applications.

This study offers a comprehensive summary of the current states as well as potential future directions of transparent conducting oxides (TCOs), particularly tin-doped indium oxide (ITO), the most readily accessible TCO on the market. Solar cells, flat panel displays (FPDs), liquid crystal displays (LCDs), antireflection (AR) coatings for airbus windows, photovoltaic and optoelectronic devices, transparent p-n junction diodes, etc. are a few of the best uses for this material.

Foot-and-mouth disease in Asia.

Foot-and-mouth disease (FMD) is a highly contagious transboundary disease prevalent across the Asian continent, affecting both wild and domestic artiodactyls. The disease is caused by a virus belonging to the Aphthovirus genus of the Picornaviridae family which is categorized into seven serotypes: C, O, A, SAT1, SAT2, SAT3, and Asia1. The virus spreads through direct and indirect contact, including semen, meat, fomites, ingestion, and aerosols.

Unexpected Victory: High-Risk Papillary Thyroid Cancer with Distant Metastases Shows Extraordinary Response to First RAI Treatment.

Papillary Thyroid Cancer (PTC) is the most prevalent type of differentiated thyroid cancer. Its incidence is growing worldwide although it has low death rates. Treatment includes surgery followed by radioactive iodine therapy.

Neutrophils extracellular traps myeloperoxidase and elastase predict cerebral vasospasms after aneurysmal subarachnoid hemorrhage.

Aneurysmal subarachnoid hemorrhage (aSAH) is a highly fatal and morbid disease. Despite successful coiling or clipping of a ruptured aneurysm, the patients suffer post-aSAH complications, including early brain injury, cerebral vasospasm (CVS), delayed cerebral ischemia (DCI), and systemic infections that mainly determine the clinical outcomes. Diagnostic biomarkers to predict accurately post-aSAH complications are needed.

Enhancing energy balance in wireless sensor networks through optimized minimum spanning tree.

Wireless sensor networks (WSNs) are important for applications like environmental monitoring and industrial automation. However, the limited energy resources of sensor nodes pose a significant challenge to the network's longevity. Energy imbalances among nodes often result in premature failures and reduced overall network lifespan.

Assessment of prevalence, antibiotic resistance, and virulence profiles of biofilm-forming isolated from raw seafood in Bangladesh.

are often resistant to different classes of antibiotics, harbor virulence determinants, and produce biofilm. The presence of in raw seafood exhibits serious public health significance. This study aimed to identify antibiotic resistance patterns and virulence factors in biofilm-forming strains extracted from seafood in Bangladesh.

Trends and determinants of caesarean section in South Asian countries: Bangladesh, Nepal, and Pakistan.

Background: The prevalence of caesarean sections (C-sections) has remarkably increased in the past few decades worldwide, especially in the lower and middle-income countries (LMICs). To our best knowledge, no studies focused on and compared the C-section scenarios of Bangladesh, Nepal, and Pakistan based on the latest demographic and health survey (DHS) data.

Objectives: To assess the trends and factors associated with C-sections in the three South Asian countries.

On the health effects of curcumin and its derivatives.

Turmeric () is an herbaceous plant that contains a phytochemical which is bright yellow and is known as curcumin. Turmeric, a member of Zingiberaceae family, has extensive application worldwide due to its beneficial medicinal attributes and is extensively used as a medicinal plant. Most people use turmeric as a spice, and it is a chief source of polyphenol curcumin.

Exploring semiconductor potential: novel boron-based TiAlC and TiAlN MAX phase composites with tunable band gaps.

This research focuses on synthesizing chemically and thermally stable novel TiAlN and TiAlC MAX phase reinforced boron-based composites using hot pressed and inert sintering processes, enabling a sizeable and wider bandgap for semiconductor applications. The study found that the MAX phase is formed from 0.2% to 2.

Novel dihydrobenzofuran derivatives: design, synthesis, cytotoxic activity, apoptosis, molecular modelling and DNA binding studies.

Pyrazoline derivatives () and () were designed and synthesized through chalcones () cyclization with NHNH/HCOOH and NHCSNHNH/CHCOOH, respectively. The molecular structures were elucidated by using various techniques such as UV-visible, FT-IR, H, C NMR spectroscopy and mass spectrometry. The purity of all synthesized compounds was checked by the liquid chromatography-mass spectrometry (LC-MS).

Comparative analysis of treatment modalities for solitary, small (≤3 cm) hepatocellular carcinoma: A systematic review and network meta-analysis of oncologic outcomes.

Background: Solitary hepatocellular carcinoma measuring ≤3 cm represents approximately 30% of hepatocellular carcinoma cases, yet treatment guidelines lack robust evidence. This study compares oncologic outcomes after ablation, liver resection, and liver transplantation for solitary, small hepatocellular carcinoma.

Methods: We systematically searched databases up to 7 February 2022, for studies including adults with solitary hepatocellular carcinoma ≤3 cm treated by any ablation, liver resection, or liver transplantation.

Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport.

Pancreatitis is an inflammatory disease of the pancreas that can arise due to various factors, including environmental risks such as diet, alcohol, and smoking, as well as genetic predispositions. In some cases, pancreatitis may progress and become chronic, leading to irreversible damage and impaired pancreatic function. Genome-wide association studies (GWAS) have identified polymorphisms at the X-linked locus as risk factors for both sporadic and alcohol-related chronic pancreatitis.

The effects of the addition of Mulligan mobilization with movement to exercise on elbow pain and function associated with lateral elbow tendinopathy.

Background: Mulligan mobilization with movement (MWM) and eccentric exercise (EE) have been shown to be effective for the treatment of chronic lateral elbow tendinopathy (LET). However, the addition of MWM to EE effects on LET remained unknown. The objective of the study was to determine the effects of adding of Mulligan mobilization with movement to eccentric exercise for the treatment of LET.

Long-Term Stability in Temporomandibular Joint Replacement: A Review of Related Variables.

The temporomandibular joint (TMJ) is a key component of the stomatognathic system, playing a major role in maintaining mandibular stability and function. Temporomandibular disorders (TMDs) are a prevalent disease in the world, with surgical treatment being reserved for complex cases or end-stage TMJ disease. A narrative review was conducted to describe the quantitative and qualitative factors that affect TMJ prosthesis stability.

Herpes stromal keratitis erodes the establishment of tissue-resident memory T cell pool in HSV-1 infected corneas.

The recurrent herpes simplex virus-1 (HSV-1) infection of the cornea can cause the development of herpes stromal keratitis (HSK). This chronic immunoinflammatory condition is a major cause of infection-induced vision loss. The previous episodes of HSK increase the risk of future recurrences in the same cornea.