[Intercropping history, pattern, and case analysis of Chinese medicinal material].

Intercropping is a traditional and widely used planting pattern, and different intercropped plants have differences in spatial distribution and morphological structure compared with monoculture. Therefore, intercropping can realize efficient acquisition of limited space resources and efficient conversion of existing resources by utilizing the principle of niche complementarity of composite groups, weakening interspecific or intra-specific competition, and enhancing their complementary growth. Intercropping of Chinese medicinal material(CMM) has experienced the evolution of more than two thousand years from its founding to inheritance and development.

Coronary computed tomography angiography for assessing the coronary artery and predicting adverse cardiovascular events in patients with thoracic malignancies.

Background: It is unclear whether the parameters derived from coronary computed tomography angiography (CCTA) can identify the impairments of coronary arteries and if they are associated with major adverse cardiovascular events (MACEs) in patients with thoracic malignancies receiving chemotherapy or chemoradiotherapy. This study aimed to investigate the longitudinal changes in coronary arteries using CCTA and to determine their association with MACEs in patients with thoracic malignancies receiving chemotherapy or chemoradiotherapy.

Methods: This cross-sectional study included consecutive patients with thoracic malignancies who received chemotherapy or chemoradiotherapy and who underwent CCTA between June 2013 and May 2019 at Chongqing University Cancer Hospital.

The association between vitamin D receptor gene polymorphism FokI and type 2 diabetic kidney disease and its molecular mechanism: a case control study.

Background: The role of the vitamin D receptor single nucleotide polymorphism FOKI (VDR-FOKI) (rs2228570) in genetic susceptibility to type 2 diabetic kidney disease (T2DKD) remains uncertain. This study investigated the relationship between VDR-FOKI and T2DKD within the Chinese Plateau Han population and analyzed the underlying mechanisms.

Methods: A total of 316 subjects were enrolled, including 44 healthy adults, 114 individuals with type 2 diabetes mellitus (T2DM), and 158 patients with T2DKD.

Acid-responsive singlet oxygen nanodepots.

The singlet oxygen carrier addresses the challenges of traditional photodynamic therapy (PDT), which relies on the presence of oxygen within solid tumors and struggles with light penetration issues. However, the inability to control the release of singlet oxygen has hindered precise treatment applications. Here, we introduce an acid-responsive singlet oxygen nanodepot (aSOND) designed to overcome this limitation.

Exploring the impact of physical exercise on mental health among female college students: the chain mediating role of coping styles and psychological resilience.

Background: Female college students are a high-risk group for psychological conflicts, and they are more likely to adopt negative coping styles under stress, which can lead to anxiety, depression, and other psychological problems, as well as pose hidden threats to the healthy development of school education and social work. Although physical exercise is an important means of effectively alleviating the psychological health of female college students, and there may be a close relationship between coping styles and psychological resilience with physical exercise and psychological health, specific ways to promote the psychological health of female college students by influencing their coping styles and enhancing their psychological resilience have yet to be explored.

Methods: The present study employed a cross-sectional design to investigate a sample of Chinese undergraduate female college students.

Identification of Taihang-chicken-specific genetic markers using genome-wide SNPs and machine learning: BREED-SPECIFIC SNPS OF TAIHANG CHICKEN.

Taihang is an indigenous breed in Hebei Province and has a long history of evolution. To uncover the genetic basis and protect the genetic resources, it is important to develop accurate markers to identify Taihang at the molecular level. In this study, a total of 137 individuals from Taihang and other 4 breeds were selected to construct a genome-wide SNP map.

Phenotypic Diversity Analysis in the Sect. ( L.) Population, an Endemic Taxon in China.

Sect. Chang belongs to the genus , which is an endemic group in China and has high research value. However, the phenotypic patterns of this taxon are complex and diverse, and the phenotypic variation in key traits is still unclear.

Accumulation and depuration of 4,5-dihydro-KmTx2 from Karlodinium veneficum in the bivalves, Mercenaria mercenaria and Sinonovacula constricta.

Bivalves (e.g., clams, oysters, mussels, scallops) are a significant part of the global diet and are harvested for their nutritional value, but as filter feeders they are susceptible to the accumulation of toxins produced by certain species of phytoplankton.

Effects of Light Spectra on Nutritional Composition in Juvenile (Lamarck 1818) and Transcriptomic Analysis.

The razor clam , a commercially important and nutritionally valuable bivalve species, has been found to display notable responses to different light spectra. While previous research has highlighted the influence of light spectra on the growth, feeding rate, and various physiological characteristics of , its impact on the biochemical composition of this species remains unclear. Herein, we investigated the proximate, fatty acid, and amino acid compositions of cultured under various light spectra, including white, violet, blue, cyan, green, yellow, red, and darkness.

Parkinson's Disease and the Microbiota-Gut-Brain Axis: Metabolites, Mechanisms, and Innovative Therapeutic Strategies Targeting the Gut Microbiota.

The human gut microbiota is diverse and abundant and plays important roles in regulating health by participating in metabolism and controlling physiological activities. The gut microbiota and its metabolites have been shown to affect the functioning of the gut and central nervous system through the microbiota-gut-brain axis. It is well established that microbiota play significant roles in the pathogenesis and progression of Parkinson's disease (PD).

Optimizing 5-aminosalicylate for moderate ulcerative colitis: expert recommendations from the Asia-Pacific, Middle East, and Africa Inflammatory Bowel Disease Coalition.

The lack of clear definition and classification for "moderate ulcerative colitis (UC)" creates ambiguity regarding the suitability of step-up versus top-down treatment approaches. In this paper, experts address crucial gaps in assessing and managing moderate UC. The Asia-Pacific, Middle East, and Africa Inflammatory Bowel Disease Coalition comprised 24 experts who convened to share, discuss and vote electronically on management recommendations for moderate UC.

Development of a Nomogram-Integrated Model Incorporating Intra-tumoral and Peri-tumoral Ultrasound Radiomics Alongside Clinical Parameters for the Prediction of Histological Grading in Invasive Breast Cancer.

Objective: To develop a comprehensive nomogram to predict the histological grading of breast cancer and further examine its clinical significance by integrating both intra-tumoral and peri-tumoral ultrasound radiomics features.

Methods: In a retrospective study 468 female breast cancer patients were analyzed from 2017 to 2020 at the Second Affiliated Hospital of Harbin Medical University. Patients were grouped into high-grade (n = 215) and low-grade (n = 253) categories based on pathological evaluation.

Autocatalysis-Integrated Bioorthogonal (Poly)Catalyst-Linked Immunosorbent Assay for Living Cell Membrane Antigens.

Immunoassay methods, notably enzyme-linked immunosorbent assays (ELISAs), renowned for their signal amplification capabilities, are extensively employed in scientific research and clinical diagnostics. However, the instability of enzymes and their sensitivity to cellular environments present significant challenges for the broad application of ELISA in living cells. In this work, we present a bioorthogonal (poly)catalysis-linked immunosorbent assay (BCLISA) designed for the detection of cell membrane antigens, which involves coupling bioorthogonal catalysts based on small molecules or polymers to antibodies.

Prediction of acute onset of chronic cor pulmonale: comparative analysis of Holt-Winters exponential smoothing and ARIMA model.

Background: The aim of this study is to analyze the trend of acute onset of chronic cor pulmonale at Chenggong Hospital of Kunming Yan'an Hospital between January 2018 and December 2022.Additionally, the study will compare the application of the ARIMA model and Holt-Winters model in predicting the number of chronic cor pulmonale cases.

Methods: The data on chronic cor pulmonale cases from 2018 to 2022 were collected from the electronic medical records system of Chenggong Hospital of Kunming Yan'an Hospital.

Practical management of mild-to-moderate ulcerative colitis: an international expert consensus.

Introduction: Although there are well-defined guidelines for the management of mild-to-moderate ulcerative colitis (UC), there are still unmet needs. For this reason, we conducted an international expert consensus to standardize the management of patients with mild-to-moderate UC and provide practical guidance to clinicians.

Areas Covered: Based on Delphi methodology, 15 statements were approved after two rounds of voting, addressing several aspects of disease management from sequencing to treatment duration, from monitoring to optimization techniques and safety profile.

Highly conductive and stable double network carrageenan organohydrogels for advanced strain sensing and signal recognition arrays.

Conductive hydrogels with excellent mechanical properties, a broad detection range, and stability in complex environments have remained a significant challenge for the development of flexible sensors. In this study, a straightforward freeze-thaw cycles strategy was developed to fabricate a polyvinyl alcohol (PVA)/carrageenan (CA)/calcium chloride (CaCl)/MXene-based double network organohydrogel (PCCME) for highly flexible and responsive strain detection across a broad temperature spectrum. The PCCME organohydrogel features multiple interactive forces including hydrogen bonding, ionic interactions, and microphase crystallization, which contribute to the organohydrogel's exceptional mechanical and electrical performance.

Modulation of Lipid Digestion by Nanoarchitectonics of Complex Interfacial Structures with Tween 80 and Lecithin.

In recent years, there has been a growing interest in regulating lipid digestion through the construction of various interfacial structures. In the present work, a series of complex interfacial structures were designed by combining Tween 80 in the aqueous phase and lecithin in the oil phase at different concentration ratios. The emulsification properties, the roles in regulating lipid digestion, and the interfacial dilatational rheological properties of the composite emulsifying systems were characterized.

Predicting biomarkers related to idiopathic pulmonary fibrosis: Robust ranking aggregation analysis and animal experiment verification.

Idiopathic pulmonary fibrosis (IPF) is a progressive and incurable lung disease characterized by unknown etiology. This study employs robust ranking aggregation to identify consistent differential genes across multiple datasets, aiming to enhance prognostic evaluation and facilitate the development of more effective immunotherapy strategies for IPF. Using the GSE10667, GSE110147, and GSE24206 datasets, the analysis identifies 92 robust differentially expressed genes (DEGs), including SPP1, IGF1, ASPN, and KLHL13, highlighted as potential biomarkers through machine learning and experimental validation.

Camellia neriifolia and Camellia ilicifolia (Theaceae) as separate species: evidence from morphology, anatomy, palynology, molecular systematics.

Background: The systematic status of sect. Tuberculata and its taxonomy have recently attracted considerable attention. However, the different bases for defining the characteristics of sect.

Chronic PM exposure disrupts intestinal barrier integrity via microbial dysbiosis-triggered TLR2/5-MyD88-NLRP3 inflammasome activation.

Background: PM, a known public health risk, is increasingly linked to intestinal disorders, however, the mechanisms of its impact are not fully understood.

Purpose: This study aimed to explore the impact of chronic PM exposure on intestinal barrier integrity and to uncover the underlying molecular mechanisms.

Methods: C57BL/6 J mice were exposed to either concentrated ambient PM (CPM) or filtered air (FA) for six months to simulate urban pollution conditions.

Linking artificial sweetener intake with kidney function: insights from NHANES 2003-2006 and findings from Mendelian randomization research.

Background: The current investigation examines the association between artificial sweetener (AS) consumption and the likelihood of developing chronic kidney disease (CKD), along with its impact on kidney function.

Methods: We utilized data from the National Health and Nutrition Examination Survey from 2003-2006 to conduct covariance analysis and weighted adjusted logistic regression, aiming to assess the association between artificial sweetener intake and CKD risk, as well as kidney function indicators. Subsequently, we employed Mendelian randomization methods to validate the causal relationship between the intake of artificial sweeteners, CKD risk, and kidney function indicators.