Publications by authors named "Ramzia I Al-Bagary"
Anal Chem Insights
June 2014
Article Synopsis
- Aqueous alkaline degradation studies were conducted on the drugs oseltamivir phosphate (OP) and valacyclovir hydrochloride (VA) using high-performance liquid chromatography (HPLC) to evaluate their stability and degradation products.
- The separations utilized different columns and mobile phases tailored for each drug, with ultraviolet detection set at specific wavelengths for improved sensitivity and accuracy.
- The degradation followed a first-order reaction, allowing for the estimation of activation energy, and the method adhered to International Conference on Harmonisation guidelines for validation purposes.
