Publications by authors named "Ramya Jayaprakash"

Kawakawa () is an endemic medicinal plant widely consumed by Māori in New Zealand. Presence of diverse biologically active phytochemicals in kawakawa may underpin its putative therapeutic anti-inflammatory properties. However, no human studies on its anti-inflammatory effects are yet undertaken.

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Article Synopsis
  • Piper excelsum (kawakawa) has been used therapeutically by Māori in New Zealand and is now popular as a beverage and functional food ingredient, with this study focusing on how its chemicals are metabolized and excreted by humans.* -
  • Two studies were conducted: one with six male volunteers to assess the bioavailability of kawakawa tea metabolites and another with 30 volunteers to explore its impact on glucose metabolism, revealing 26 significant urinary metabolites linked to kawakawa tea consumption.* -
  • The findings indicate that various kawakawa compounds are bioavailable, undergoing metabolic changes in the body, with some metabolites being associated with specific components of the tea.*
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The chemical profiles of kawakawa () leaves were analysed through targeted and non-targeted LC-MS/MS. The phytochemical profile was obtained for both aqueous extracts representative of kawakawa tea and methanolic extracts. Sixty-four compounds were identified from eight leaf sources including phenylpropanoids, lignans, flavonoids, alkaloids and amides.

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Article Synopsis
  • Piper excelsum, or kawakawa, is a native New Zealand shrub important to Māori culture, known for its medicinal properties, with its fruits and leaves often consumed due to their health benefits.
  • A pilot study tested kawakawa tea's effects on glucose metabolism by comparing high-dose and low-dose tea against water in male participants, revealing lower glucose and insulin levels after consuming the higher dose.
  • Results suggest that kawakawa tea may improve post-meal glucose metabolism and insulin sensitivity, indicating the need for further long-term research on its health impacts.
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Proteins from fresh New Zealand green-lipped mussels were hydrolyzed for 240 min using pepsin and alcalase. The extent of the hydrolysis, antioxidant, antimicrobial, and angiotensin-converting enzyme (ACE) inhibitory activities of each protein hydrolysate were investigated. Peptides obtained from pepsin hydrolysis after 30 min, named GPH, exhibited the highest antioxidant and ACE inhibitory activity, but no antimicrobial activity.

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Petroleum based products are the major source of energy for industries and daily life. Leaks and accidental spills occur regularly during the exploration, production, refining, transport, and storage of petroleum and petroleum products. In the present study we isolated the bacteria from diesel contaminated soil and screened them for diesel biodegradation capacity.

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