Publications by authors named "Ramune Zilinskaite-Tamasauske"
Article Synopsis
- The study aimed to explore how fibrosis-related genes in obstructed ureteral tissue relate to renal damage markers and preoperative renal scans.
- Researchers collected urine and blood samples pre-surgery, analyzing various biomarkers and gene expressions from obstructed tissue samples.
- The results showed certain negative correlations between urinary albumin and expressions of TGFβ1 and VEGFA in the obstructive tissue, but overall, no direct links were found between gene expressions and renal damage biomarkers.
To enhance the treatment of patients' urethral defects, such as strictures and hypospadias, we investigated the potential of using artificial urethral tissue. Our study aimed to generate this tissue and assess its effectiveness in a rabbit model. Two types of bioprinted grafts, based on methacrylated gelatin-silk fibroin (GelMA-SF) hydrogels, were produced: acellular, as well as loaded with autologous rabbit stem cells.
View Article and Find Full Text PDFCongenital ureteral stenosis is one of the leading causes of impaired urinary drainage and subsequent dilatation of the urinary collecting system, known as hydronephrosis or ureterohydronephrosis. The mechanism that leads to obstruction is not clearly known. Multiple studies in rat models have shown increased angiotensin II and TGFβ levels in obstructed ureteral tissue.
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