Publications by authors named "Ramtin Omid-Shafaat"
Article Synopsis
- Type 2 diabetes mellitus (T2DM) can lead to severe complications, including diabetic nephropathy (DN), which is linked to liver-derived factors known as hepatokines, particularly Angiopoietin-Like Protein 3 (ANGPTL3).
- In a study involving 60 healthy individuals, 60 T2DM patients, and 61 DN patients, researchers measured serum levels of ANGPTL3, IL-6, and TNF-α, finding significantly higher ANGPTL3 levels in both T2DM and DN patients compared to controls, with DN patients showing the highest levels.
- The results suggest that ANGPTL3 is associated with renal dysfunction and lipid metabolism, potentially playing a
Purpose: Fluoropyrimidines, the major chemotherapeutic agents in various malignancies treatment, are metabolized by dihydropyrimidine dehydrogenase (DPD). DPD deficiency can lead to severe and sometimes fatal toxicity. In the present study, we developed a simple protocol to detect the DPYD*2A variant.
View Article and Find Full Text PDFBackground: Recently, measurement of serum circular RNAs (circRNAs) as a non-invasive tumor marker has been considered more. We designed the present study to investigate the diagnostic efficiency of serum Circ-ELP3 and Circ-FAF1, separately and simultaneously, for diagnosis of patients with breast cancer.
Methods: Seventy-eight female patients diagnosed as primary breast cancer participated in this study.