The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review.

Objective: Asthma is associated with bronchial hyperresponsiveness, assessed by bronchial provocation tests such as the mannitol test. We aimed to assess the data on sensitivity and specificity of the mannitol test in diagnosing asthma.

Data Sources: We searched electronically the Medline, Embase and Central databases from 1997 to 2019.

San Francisco Syncope Rule to predict short-term serious outcomes: a systematic review.

Background: The San Francisco Syncope Rule has been proposed as a clinical decision rule for risk stratification of patients presenting to the emergency department with syncope. It has been validated across various populations and settings. We undertook a systematic review of its accuracy in predicting short-term serious outcomes.