Publications by authors named "Ramon E"

Article Synopsis
  • - The study investigates the reliability of two sequencing methods, 16S rRNA gene and shotgun metagenomic sequencing, in profiling gut microbiota associated with colorectal cancer (CRC) using 156 stool samples from different patient groups.
  • - Results indicate that 16S captures only part of the microbiota detected by shotgun, with notable differences in abundance, diversity, and taxonomic resolution due to varying reference databases.
  • - Both techniques can reveal microbial signatures linked to CRC, but no clear superiority of one method over the other was established, suggesting they provide complementary insights into gut microbiota analysis.
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Given the current maturity of printed technologies, Organic Thin-Film Transistors (OTFT) still show high initial variability, which can be beneficial for its exploitation in security applications. In this work, the process-related variability and aging of commercial OTFTs have been characterized to evaluate the feasibility of OTFTs-based Physical Unclonable Functions (PUFs) implementation. For our devices, -based PUFs show good uniformity and uniqueness.

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Article Synopsis
  • Spontaneous portosystemic shunts (SPSS) often develop in patients with cirrhosis, and their progression over time, especially in relation to treatments like alcohol abstinence or antiviral therapy for HCV, was the focus of this study.
  • In a cohort of 617 patients followed over an average of 63 months, there was a noticeable increase in the severity of SPSS, with larger and more frequent shunts observed, particularly among non-cured patients who experienced poorer liver function and more complications.
  • Overall, while interventions like quitting alcohol or successful HCV treatment improved liver health and reduced complications, SPSS continued to exist and worsen, albeit at a slower rate in patients who were cured.
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Colorectal cancer (CRC), the third most common cancer globally, has shown links to disturbed gut microbiota. While significant efforts have been made to establish a microbial signature indicative of CRC using shotgun metagenomic sequencing, the challenge lies in validating this signature with 16S ribosomal RNA (16S) gene sequencing. The primary obstacle is reconciling the differing outputs of these two methodologies, which often lead to divergent statistical models and conclusions.

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Maternal, placental, and neonatal factors were compared between infants born at ≤29 weeks of gestational age with admission hyperthermia (>37.5C) and euthermia (36.5-37.

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Background: In Nigeria, there have been reports of widespread multiple antimicrobial resistance (AMR) amongst Salmonella isolated from poultry. To mitigate the impact of mortality associated with Salmonella on their farms, farmers resort to the use of antimicrobials without sound diagnostic advice. We conducted this study to describe the AMR patterns, mechanisms and genetic similarities within some Salmonella serovars isolated from different layer farms.

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Trace metals are essential elements that play key roles in a number of biochemical processes governing human visual physiology in health and disease. Several trace metals, such as zinc, have been shown to play important roles in the visual phototransduction process. In spite of this, there has been little research conducted on the direct effect of trace metal elements on the visual photoreceptor rhodopsin.

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Acne is a common chronic skin condition with serious physical and psychosocial consequences. In some cases, the appearance of pimples, whiteheads, or blackheads on the face, neck, and back may lead to scarring, disfiguring, depression, frustration, and anxiety in patients. Current treatments rely on antibiotics to eradicate (), the bacterium responsible for this skin condition.

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Background & Aims: Clinically significant portal hypertension (CSPH) is a landmark in the natural history of cirrhosis, influencing clinical decisions in patients with hepatocellular carcinoma (HCC). Previous small series suggested that splanchnic volume measurements may predict portal hypertension. We aimed to evaluate whether volumetry obtained by standard multidetector computerised tomography (MDCT) can predict CSPH in patients with HCC.

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Objective: Cirrhosis is characterized by the complex interplay among biological, histological and haemodynamic events. Liver and spleen remodelling occur throughout its natural history, but the prognostic role of these volumetric changes is unclear. We evaluated the relationship between volumetric changes assessed by multidetector computerised tomography (MDCT) and landmark features of cirrhosis.

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Background: Although electrocardiogram (ECG) can detect heart rate (HR) faster compared to pulse oximetry, it remains unknown if routine use of ECG for delivery room (DR) resuscitation reduces the time to stabilization in preterm infants.

Methods: Neonates <31 weeks' gestation were randomized to either an ECG-displayed or an ECG-blinded HR assessment in the DR. HR, oxygen saturation, resuscitation interventions, and clinical outcomes were compared.

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Enzyme inks can be inkjet printed to fabricate enzymatic biosensors. However, inks containing enzymes present a low shelf life because enzymes in suspension rapidly lose their catalytic activity. Other major problems of printing these inks are the non-specific adsorption of enzymes onto the chamber walls and stability loss during printing as a result of thermal and/or mechanical stress.

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The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e.

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Article Synopsis
  • - The study aims to improve the classification and treatment of systemic autoimmune diseases by identifying molecular clusters, moving beyond traditional clinical diagnosis methods.
  • - Researchers analyzed blood samples from 955 patients and 267 healthy controls, discovering four distinct clusters: three linked to inflammatory responses and one related to low disease activity associated with healthy controls.
  • - The findings suggest that these molecular clusters are stable over time and can aid in understanding disease mechanisms and improving treatment strategies, potentially changing how systemic autoimmune diseases are approached in clinical settings.
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Background: Solitary fibrous tumor is an unusual fibroblastic mesenchymal neoplasm typically described in the pleura. It may appear anywhere with a varied anatomic distribution and essentially it can develop from any soft tissue or visceral location. Its course is usually indolent and it rarely causes distant metastases, so it has a prolonged survival rate.

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Uranium ore is mined and milled to produce uranium ore concentrate (UOC), a regulated product of the nuclear fuel cycle. Diversion of UOC from the fuel cycle into possible weapons production is a key concern in global nonproliferation efforts. As such, the ability to trace the origin of seized nuclear materials is imperative to law enforcement efforts.

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Targeted bactericide nanosystems hold significant promise to improve the efficacy of existing antimicrobials for treatment of severe bacterial infections, minimizing the side effects and lowering the risk of the development of antibiotic resistance. In this work, we developed antibody-functionalized nanocapsules (NCs) containing antibacterial essential oil (EO) for selective and effective eradication of . Antibacterial EO NCs were produced via self-assembly nanoencapsulation in the plant-derived protein zein.

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Background: Normal birth has major benefits for women and infants. Nevertheless, during the last few decades, the advancement in technology and an increasing domination of obstetrician-led childbirths have resulted in the medicalization of childbirth. Midwives are interested in amending this trend and aim to support women to achieve the best possible birth experience for them.

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An unusual mortality of wild boars occurred in Italy from 2012 to 2015 due to Salmonella Choleraesuis infection. In order to confirm the occurrence of an outbreak of S. Choleraesuis in wild boars and to epidemically characterise the unique S.

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Introduction: Macrovascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is a very poor prognostic factor. Treatment in such cases is still a matter of debate. The goal of this study is to assess short- and long-term results of liver resection and thrombectomy in a series of patients with HCC and MVI.

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Background: Antiretroviral drugs are a very effective therapy against HIV infection. However, the high mutation rate of HIV permits the emergence of variants that can be resistant to the drug treatment. Predicting drug resistance to previously unobserved variants is therefore very important for an optimum medical treatment.

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Until recently, the analysis and identification of nuclear fuel pellets in the context of a nuclear forensics investigation have been mainly focused on macroscopic characteristics, such as fuel pellet dimensions, uranium enrichment, and other reactor-specific features. Here, we report microscale isotopic heterogeneity observed in different fuel pellet fragments that were characterized in situ by nanoscale secondary ion mass spectrometry (NanoSIMS). The materials analyzed include fuel fragments obtained as part of the Collaborative Materials Exercise (CMX-4) organized by the Nuclear Forensics International Technical Working Group (ITWG), as well as a fuel pellet fragment from a commercial power reactor.

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serovar 1,4,[5],12:i:- has emerged over the last two decades as one of the most common serovars causing human salmonellosis in Europe. It is supposed to originate from serovar Typhimurium due to antigenic and genotypic similarities between the two serovars. Due to the high level of similarity, the multilocus variable-number tandem repeat analysis (MLVA) protocol designed for Typhimurium routine typing is commonly used also for the characterization of 1,4,[5],12:i.

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