Benzobicyclo[3.2.1]octene Derivatives as a New Class of Cholinesterase Inhibitors.

A library of amine, oxime, ether, epoxy and acyl derivatives of the benzobicyclo[3.2.1]octene were synthesized and evaluated as inhibitors of both human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).