Persistent disruption of overexpectation learning after inactivation of the lateral orbitofrontal cortex in male rats.

Rationale And Objective: Learning to inhibit acquired fear responses is fundamental to adaptive behavior. Two procedures that support such learning are extinction and overexpectation. In extinction, an expected outcome is omitted, whereas in overexpectation two individually trained cues are presented in compound to induce an expectation of a greater outcome than that delivered.