Publications by authors named "Ramirez-Iglesias M"
Introduction: Despite the fact that the frequency of hypolactasia and lactose intolerance is similar in both chronic idiopathic ulcerative colitis patients and the general population, the elimination of dairy products from the patient's diet is a habitual recommendation. Hypolactasia is common in Mexico, but its relation to chronic idiopathic ulcerative colitis has not been established.
Aims: To evaluate lactose digestion and lactose intolerance in persons with chronic idiopathic ulcerative colitis.
Article Synopsis
- Researchers aimed to enhance the prognosis of acute pancreatitis by evaluating the effectiveness of four serum markers (CRP, IL-6, IL-10, PAP) compared to Ranson's score.
- A study of 71 patients revealed that severe cases showed higher levels of all markers, with IL-10 demonstrating greater predictive accuracy than Ranson's score.
- Timing of patient admission significantly affected the markers' predictive power, with IL-6, IL-10, and PAP being more accurate within the first 48 hours, while CRP excelled afterward, indicating the importance of considering the time of evolution in prognosis.
Background And Aims: Recent studies have shown that celiac disease (CD) could affect 0.5% to 3% of the general population, including Mexican Mestizos, which represents a complex mixture of genetics, and constitutes the core of Mexican and Latin American populations. However, the association between CD and other conditions, specifically type-1 diabetes mellitus, in this population remains unknown.
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- This study links specific DNA variants to alcohol metabolism related to alcoholism in individuals of Otomi Mexican Indian ancestry.
- It compared 59 chronic alcoholics to 59 nonalcoholics, finding a significant association with a genetic polymorphism in the CYP2E1 gene.
- The results suggest that the A1 variant of CYP2E1 may increase susceptibility to alcoholism and potentially contribute to liver cirrhosis in this ethnic group.
Introduction/aim: In North America and Europe, the prevalence of celiac disease (CD) might be much greater than expected in previous estimates. Until recently, the prevalence of CD in Latin America remained largely unknown. So far, information regarding CD in Mexico is limited, and it is still considered a rare disease.
View Article and Find Full Text PDFAim: To evaluate the relationship between leptin and systemic inflammation in acute pancreatitis.
Methods: Consecutive patients with acute pancreatitis were included. Body mass index and serum samples were obtained at admission.
The cellular and humoral natural immune response induced by hepatitis C virus (HCV) is commonly unable to eradicate the virus. HCV is a highly mutable, hepatotropic RNA virus that causes acute and chronic hepatitis, an infection that involves the production of various cytokines. The aim of the study is to analyse the expression of pro-inflammatory cytokines IL-1beta, TNF-alpha, IFN-gamma and the chemokine CXCL8 (IL-8) in liver tissue and their expression and secretion in PBMC of patients with chronic hepatitis C (CHC), in response to pentoxyfilline (PTX).
View Article and Find Full Text PDFBackground: Bombesin is a peptide that was initially isolated from frog skin and which belongs to a large group of neuropeptides with many biological functions. The human equivalent is gastrin-releasing peptide (GRP), whose receptors are over-expressed in a variety of malignant tumours.
Aim: To prepare a HYNIC-[Lys 3]-bombesin analogue that could be easily labelled with 99mTc from lyophilized kit formulations and to evaluate its potential as an imaging agent for GRP receptor-positive tumours.