Neuroprotective Effect of New Nanochelating-Based Nano Complex, ALZc3, Against Aβ -Induced Toxicity in Rat: a Comparison with Memantine.

Purpose: The current drugs for Alzheimer's disease (AD) are only used to slow or delay the progression of the pathology. So using a novel technology is a necessity to synthesize more effective medications to control this most common cause of dementia. In this study, using nanochelating technology, ALZc3 was synthesized and its therapeutic effects were evaluated in comparison with memantine on a well-known rat model of AD, which is based on Amyloid-βeta (Aβ) injection into the brain.