The effect of (green tea) with its active compound EGCG on neuronal cell necroptosis in middle cerebral artery occlusion (MCAO) model.

Objectives: To determine the inhibition effect of (EGCG) and green tea extract on neuronal necroptosis based on necroptosis morphology.

Methods: study was performed on male middle cerebral artery occlusion (MCAO) model divided into five groups, MCAO-control groups, EGCG 10 mg/kg BW/day, EGCG 20 mg/kg BW/day, EGCG 30 mg/kg BW/day, and green tea extract 30 mg/kg BW/day for 7 days treatment. MCAO model was made by modification method using Bulldog clamp.