Publications by authors named "Rami Jubeh"

Background: 'Simultaneous CardioFlow optimization' represents an innovative technique that effectively enhances post-pacing haemodynamic recovery during transcatheter aortic valve replacement. This technique was applied in two high-risk patients presenting with severe left main trunk stenosis with concomitant severe aortic stenosis (AS) and left ventricular dysfunction (LVD).

Case Summary: An 86-year-old and a 96-year-old patient were admitted with myocardial infarction.

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  • Platelets have a significant impact on aortic stenosis (AS) and patients undergoing transcatheter aortic valve implantation (TAVI), prompting an analysis of their indices in relation to AS stages.
  • In a study involving 220 TAVI patients, they were categorized into 5 AS stages based on cardiac damage, revealing a correlation between higher mean platelet volume (MPV) and advanced AS staging, as well as lower hemoglobin levels.
  • The findings indicate that while MPV and immature platelet fraction (IPF) show variations across stages, only MPV and body mass index (BMI) were significant predictors of higher AS staging in the logistic regression analysis.
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  • The trial tested the ShortCut device, aimed at improving safety and effectiveness before TAVI in patients at risk for coronary artery obstruction.
  • In a study with 60 patients, 100% successfully underwent leaflet splitting with minimal procedure time and high safety rates; 98.3% were free from major adverse events like stroke or mortality at discharge.
  • The results suggest that using ShortCut for modifying failed bioprosthetic aortic valves is safe and leads to positive outcomes for patients facing coronary obstruction during TAVI.
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Importance: Rapid reperfusion during primary percutaneous coronary intervention (PCI) is associated with improved outcomes among patients with ST-elevation myocardial infarction (STEMI). Although attempts at reducing the time from STEMI diagnosis to arrival at the catheterization laboratory have been widely investigated, intraprocedural strategies aimed at reducing the time to reperfusion are lacking.

Objective: To evaluate the effect of culprit lesion PCI before complete diagnostic coronary angiography (CAG) vs complete CAG followed by culprit lesion PCI on reperfusion times among patients with STEMI.

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Introduction: Immature platelets or reticulated platelets are newly released thrombocytes. They can be identified by their large size and high RNA cytoplasm concentration. Immature platelet fraction (IPF) represents the percentage of immature circulative platelets relative to the total number of platelets.

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Background: Coronary artery obstruction is a life-threatening complication of transcatheter aortic valve replacement (TAVR) procedures. Current preventive strategies are suboptimal.

Objectives: The aim of this study was to describe bench testing and clinical experience with a novel device that splits valve leaflets that are at risk for causing coronary obstruction after TAVR, allowing normal coronary flow.

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  • Cardiogenic shock, often following a heart attack, leads to poor outcomes and high mortality rates, making timely treatment critical.
  • Early revascularization of the affected blood vessel is the best approach to improve survival, but it doesn’t eliminate the risk of death.
  • Temporary circulatory support devices can help manage the condition, yet there is a lack of solid evidence on their effective use, highlighting the need for expert care from multiple disciplines.
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  • * Key factors that predict non-IRA CAD include being male, over 50 years old, and having diabetes, whereas smoking and a family history of CAD are linked to IRA-only CAD.
  • * Patients with non-IRA CAD experienced higher mortality rates both in the short-term (30 days) and long-term (1 and 5 years) compared to those with IRA-only CAD,
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Background: Measuring fractional flow reserve (FFR) with a pressure wire remains underutilized because of the invasiveness of guide wire placement or the need for a hyperemic stimulus. FFR derived from routine coronary angiography (FFR) eliminates both of these requirements and displays FFR values of the entire coronary tree. The FFR Accuracy versus Standard FFR (FAST-FFR) study is a prospective, multicenter, international trial with the primary goal of determining the accuracy of FFR.

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