Background: About 10-20% of patients with anal squamous cell carcinoma (SCCa) present with metastatic disease and are usually treated with systemic chemotherapy. However, primary tumor control is crucial as local failure is associated with significant morbidity. Using the largest cohort to date, we report the impact of local therapy on survival among patients with metastatic anal SCCa.
View Article and Find Full Text PDFBackground: Randomized controlled trials have evaluated the efficacy of low-dose CT (LDCT) lung cancer screening on lung cancer (LC) outcomes.
Objective: Meta-analyze LDCT lung cancer screening trials.
Methods: We identified studies by searching PubMed, Google Scholar, the Cochrane Registry, ClinicalTrials.
Background: Patients with CML treated with TKI can have a life expectancy comparable to that of the general population. Due to the extended duration of TKI administration, treatment discontinuation has been increasingly sought.
Methods: Medical records of 100 patients with CML who were in MR and discontinued their TKI outside clinical trials were reviewed.