Up versus down: Does cuff spine orientation affect early adherence to upper airway stimulation?

Purpose: Upper airway stimulation (UAS) is a treatment option for moderate-to-severe OSA, in which electrical stimulation is applied to the hypoglossal nerve via an electrode cuff. In this study, we assess the effect of electrode cuff positioning on UAS outcomes, in particular device adherence.

Methods: Patients at a single academic institution who met the Food and Drug Administration criteria for UAS between 2016 and 2021 were included.

Assessing the Reporting Quality of Machine Learning Algorithms in Head and Neck Oncology.

Objective: This study aimed to assess reporting quality of machine learning (ML) algorithms in the head and neck oncology literature using the TRIPOD-AI criteria.

Data Sources: A comprehensive search was conducted using PubMed, Scopus, Embase, and Cochrane Database of Systematic Reviews, incorporating search terms related to "artificial intelligence," "machine learning," "deep learning," "neural network," and various head and neck neoplasms.

Review Methods: Two independent reviewers analyzed each published study for adherence to the 65-point TRIPOD-AI criteria.

Cutaneous Squamous Cell Carcinoma of the Head and Neck: Pathological Features and What They Mean for Prognosis and Treatment.

Cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers worldwide, with an incidence that has increased over the past 30 years. Although usually curable with excision, cSCC can become widely metastatic and aggressive with poor outcomes. Whereas the clinical and radiographic extent of any cancer will always guide selection of treatment modality, pathological features of cSCC also play an important role in determining prognosis and, subsequently, the need for further therapy.

Sinonasal NUT carcinoma: A consecutive case series and systematic review.

Background: Sinonasal NUT carcinoma is an extremely rare, lethal malignancy with limited literature.

Methods: A case series was conduction of all patients with sinonasal NUT carcinoma at a single institution between 2010 and 2022. Survival and associated were evaluated.

Non-Melanoma Skin Cancer Detection in the Age of Advanced Technology: A Review.

Skin cancer is the most common cancer diagnosis in the United States, with approximately one in five Americans expected to be diagnosed within their lifetime. Non-melanoma skin cancer is the most prevalent type of skin cancer, and as cases rise globally, physicians need reliable tools for early detection. Artificial intelligence has gained substantial interest as a decision support tool in medicine, particularly in image analysis, where deep learning has proven to be an effective tool.

Identification and characterization of virulent Ah17 from infected in river Cauvery and in vitro evaluation of shrimp chitosan.

, an inhabitant in the aquatic ecosystem is considered as an important foodborne bacterial zoonotic pathogen in aquaculture. The present study aimed to identify virulent from naturally infected in river Cauvery and in vitro evaluation of shrimp chitosan. Rimler Shotts (RS) and blood agar medium identified the presence of pathogenic sp.

Synthesis of germanium nanocrystals from solid-state disproportionation of a chloride-derived germania glass.

Germanium nanocrystals (Ge NCs) have potential to be used in several optoelectronic applications such as photodetectors and light-emitting diodes. Here, we report a solid-state route to synthesizing Ge NCs through thermal disproportionation of a germania (GeOX) glass, which was synthesized by hydrolyzing a GeCl2·dioxane complex. The GeOX glass synthesized in this manner was found to have residual Cl content.

A Schiff's base receptor for red fluorescence live cell imaging of Zn ions in zebrafish embryos and naked eye detection of Ni ions for bio-analytical applications.

An interesting dual chemoreceptor (QAMP) was synthesized to quantify the presence of two environmentally as well as biologically important Zn/Ni ions in a highly selective manner using different analytical techniques. The fluorescence profile was enhanced to 663 nm (red region) due to the formation of its 1 : 1 complex with Zn at room temperature even in the presence of other interfering ions such as Cd and Hg. Moreover, it exhibits excellent chromo-isomerism with Ni ions.

Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008-2014.

Objective: There have been no long-term studies on trends in antibiotic resistance (ABR) on a national scale in India. Using a private laboratory network, the ABR patterns of organisms most commonly associated with bacteremia, obtained from patients across India between 2008 and 2014, were examined.

Methods: A retrospective study of patient blood cultures collected over a 7-year period (January 1, 2008-December 31, 2014) was conducted.

New free radical scavenging neolignans from fruits of Piper attenuatum.

Objective: The aim was to study and identify free radicals scavenging and antihyperglycemic principles in fruit of Piper attenuatum.

Materials And Methods: Bioassay guided identification of extracts possessing potent free radical scavenging activity, and isolation of compounds was done. Chloroform extract of P.

Convenient one-pot synthesis, anti-mycobacterial and anticancer activities of novel benzoxepinoisoxazolones and pyrazolones.

Series of new benzoxepinoisoxazolones 4a-d and pyrazolones 6a-t were prepared by the cyclocondensation of substituted (E)-ethyl 3-oxo-2,3-dihydrobenzo[b]oxepine-4-carboxylates 3a-d with hydroxylamine hydrochloride and phenylhydrazine hydrochlorides 5a-k. Synthesized compounds were screened for their in vitro anti-mycobacterial activity and anticancer activity. Ten compounds displayed good anti-mycobacterial activity, among these; compound 4d and 6b found to be potent when compared to standard drug isoniazid.

Predicted concentrations of biocides from antifouling paints in Visakhapatnam Harbour.

The concentrations of biocides leached from antifouling coatings are monitored in most of the developed countries. However, in India and many other developing countries, there is very little data available on the concentrations of biocides in ports and harbours. The first step was to obtain the order of magnitude levels of concentrations of biocides in the marine environment of the Visakhapatnam Harbour, and the MAM-PEC (Marine Antifoulant Model to Predict Environmental Concentrations) model was used to predict these values.

Occurrence and seasonal variation of bacterial indicators of faecal pollution along Thoothukudi Coast, Tamil Nadu.

Theprevalence and seasonal variation of bacterial indicators of faecal pollution such as total coliform bacteria, faecal coliform bacteria, Escherichia coli and faecal streptococci were investigated in samples of water and beach sand from the four fish landing centres of Thoothukudi. Further the samples were screened for Salmonella to study the reliability of faecal indicator bacteria as an index of human pathogenic bacteria. Total coliform bacteria, faecal coliform bacteria and Escherichia coli were isolated from all four landing centres from undetectable to the maximum detectable level of over Most Probable Number 140 throughout the year with no obvious seasonal variation.

Inhibition of protein kinase C by the tyrosine kinase inhibitor erbstatin.

We examined the tyrosine kinase inhibitor erbstatin and several derivatives for their ability to inhibit serine/threonine protein kinases in vitro. Erbstatin was found to inhibit protein kinase C (PKC) with an IC50 of 19.8 +/- 3.

Footprint of the sigma protein.

Escherichia coli RNA Polymerase is a multi-subunit enzyme that catalyzes RNA synthesis, using DNA as a template. The sigma subunit of this enzyme plays an important role in the recognition of promoter sites on DNA. Using DNase I footprinting, we have found that in the absence of the other subunits, sigma binds specifically to the bacteriophage lambda PR promoter DNA sequence.