Publications by authors named "Ramesh Krishnamoorthy"
Article Synopsis
- P2Y(12) receptors are crucial for platelets to activate and clump together in response to ADP, and INS50589 is a selective antagonist being tested for its ability to modulate this process safely.*
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- In a study with 36 healthy volunteers, INS50589 was infused at different doses, showing a dose-dependent reduction in platelet activation and increased bleeding time, but no significant changes in other clotting tests.*
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- The effects of INS50589 appear to wear off relatively quickly after stopping the infusion, making it a promising option for controlled platelet modulation in cardiovascular treatments without lasting side effects.*
