Publications by authors named "Rambabu Anandam"
Chem Biodivers
April 2023
Article Synopsis
- - The study explores an innovative reaction process involving the Oxa-Michael addition of penta-substituted phenols to a tethered enone, utilizing iodine as an oxidizing agent, resulting in the successful synthesis of ten C-dimethylated flavones with yields ranging from 60-89%.
- - Subsequently, the efficacy of these compounds against Mycobacterium tuberculosis was assessed using the Microplate Alamar Blue test, revealing two compounds (10e, 10h) with significant antibacterial sensitivity.
- - Anticancer properties were evaluated in human lung cancer cell lines (A549) using the MTT assay, where four flavones exhibited notable activity with IC values between 39 and 48 μM,
