Publications by authors named "Ramasamy Pasiyappazham"

Article Synopsis
  • Chitosan, a biopolymer from chitin, has beneficial properties like antibacterial and biodegradability, making it a good candidate for dental treatments, especially when enhanced by phosphorylation from cuttlebone.
  • The study aimed to create phosphorylated chitosan from cuttlebone and test its effectiveness against oral pathogens at different concentrations.
  • Results showed that 100% phosphorylated chitosan effectively inhibited certain bacteria, indicating its potential as a dental care material, particularly against infections.
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Chitosan (Ch) and acid-soluble collagen (ASC) from Doryteuthis singhalensis gladius were isolated to test their osteogenic, angiogenic, and wound healing capabilities in male Wistar rats. The results of the study showed that the ASC yield was 18.58 %, the total protein content was 86.

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The development of self-preserving personal care cosmetics represents a significant advancement in the cosmetics industry, offering safer and more natural alternatives to consumers. This study focused on the preparation of such formulations using multifunctional ingredients along with other cosmetic components. Five unique multifunctional ingredients (MFIs) were identified based on their antimicrobial properties: sodium coco PG-dimonium chloride phosphate, ricinoleic acid, palmitoleic acid, raspberry ketone, and sorbitan caprylate.

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Background This study investigated the anticoagulant properties of sulfated chitosan derived from the internal bone of the spineless cuttlefish . Chitosan, a biopolymer, is used in various biomedical applications including anticoagulation. Sulfation of chitosan enhances its biological activity, making it a potential therapeutic agent.

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Background: Dental materials with dentine regenerative properties are preferred over conventional materials. Calcium silicate cements, such as Biodentine, are bioactive and offer excellent sealing ability, making them ideal for various dental treatments.

Objectives: This study aimed to fabricate bioactive calcium silicates infused with titanium (Ti) and strontium (Sr) to optimize their neo-angiogenic, antimicrobial, and regenerative properties while maintaining mechanical stability.

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Background This study aimed to isolate linear polysaccharides from cuttlebone with the objective of evaluating their ability to scavenge free radicals. By providing new natural components for pharmaceutical and functional food uses, this research advances our understanding of the potential health benefits of polysaccharides originating from marine sources and their antioxidant properties. Objective The objective of the study is to isolate a linear polysaccharide chitosan from cuttlebone (produced by the partial deacetylation of chitin), characterize its structure using fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD), and explore the isolated polysaccharide's free radical scavenging potential.

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Heavy metal pollution has significant impacts on aquatic fauna and flora. It accumulates in marine organisms, both plants and animals, which are then consumed by humans. This can lead to various health problems, such as organ damage and the development of cancer.

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Background: Scientists are currently investigating ecologically sound and enduring techniques for nanoparticle production. Utilizing natural sources such as plant extracts provides an environmentally friendly and economically efficient method. , also referred to as the gray mangrove, is predominantly located in coastal regions.

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Background: Marine macroalgae is consumed by individuals in several regions, including Scandinavia, Great Britain, Ireland, China, and Japan; in Japan, it is commonly referred to as aosa. Copper nanoparticles are primarily composed of copper and exhibit a size distribution ranging from 1 to 100 nm. Copper nanoparticles can be synthesized using chemical or natural means, similar to other nanoparticle variants.

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Introduction The field of nanotechnology is currently being extensively researched. Nanoparticles (NPs) are used in many fields, such as engineering and medicine, owing to their nanoscale dimensions. Zinc (Zn) appears to be the most desirable metal NP, as it is being applied in various drug delivery systems and other fields.

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The primary natural resource we use in our daily lives for a variety of activities is freshwater for drinking and various developmental goals. Furthermore, the pace of human population increase worldwide is rising rapidly and has a great impact on the Earth's natural resources. Natural water quality has diminished owing to various anthropogenic activities.

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Microbially influenced corrosion (MIC) of metals is an important industrial problem, causing 300-500 billion dollars of economic loss worldwide each year. It is very challenging to prevent or control the MIC in the marine environment. Eco-friendly coatings embedded with corrosion inhibitors developed from natural products may be a successful approach for MIC prevention or control.

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The rapid advancement of molecular research has contributed to the discovery of 'Lectin', a carbohydrate-binding protein which specifically interacts with receptors on surface glycan moieties that regulate various critical cellular activities. The first animal lectin reported was 'the asialoglycoprotein receptor' in mammalian cells which helped analyze how animal lectins differ in glycoconjugate binding. Animal lectins are classified into several families, depending on their diverse cellular localization, and the binding specificities of their Carbohydrate-Recognition Domain (CRD) modules.

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The prevalence of infectious diseases in the aquaculture industry and a limited number of safe and effective oral vaccines has imposed a challenge not only for fish immunity but also a threat to human health. The availability of fish oral vaccines has expanded recently, but little is known about how well they work and how they affect the immune system. The unsatisfactory efficacy of existing oral vaccinations is partly attributable to the antigen degradation in the adverse gastrointestinal environment of fishes, the highly tolerogenic gut environment, and inferior vaccine formulation.

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The present work aimed to synthesis of chitin, chitosan and sulfation of chitosan from cuttlebone of cuttlefish . Principally chitin was extracted through sequential processes of demineralisation and deproteinzation. Then chitosan was synthesized by a deacetylation and finally sulfated at semi-heterogeneous condition using chlorosulfonic acid in ,-dimethylformamide.

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Worldwide, reef building corals are being degraded due to increasing anthropogenic pressure, and as a result, macroalgal cover is being increased. Hence, mechanism of coral-algal interaction, differential coral response to algal overgrowth, is critical from every geographical location to predict future coral dynamics. This paper documents the frequency of coral-algal (Halimeda) interactions, differential coral response to algal interaction.

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Sponges are sessile benthic filter-feeding animals, which harbor numerous microorganisms. The enormous diversity and abundance of sponge associated bacteria envisages sponges as hot spots of microbial diversity and dynamics. Many theories were proposed on the ecological implications and mechanism of sponge-microbial association, among these, the biosynthesis of sponge derived bioactive molecules by the symbiotic bacteria is now well-indicated.

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The discovery of genes responsible for the production of bioactive metabolites via metabolic pathways combined with the advances in synthetic biology tools, has allowed the establishment of numerous microbial cell factories, for instance the yeast cell factories, for the manufacture of highly useful metabolites from renewable biomass. Genome mining and metagenomics are two platforms provide base-line data for reconstruction of genomes and metabolomes which is based in the development of synthetic/semi-synthetic genomes for marine natural products discovery. Engineered biofilms are being innovated on synthetic biology platform using genetic circuits and cell signalling systems as represillators controlling biofilm formation.

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Type I collagen from outer skin of was extracted and partially characterized. Yield of Acid Soluble Collagen (ASC) and Pepsin Soluble Collagen (PSC) were calculated as 1.66% and 3.

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