Publications by authors named "Ramandeep Banga"
Background: Small molecule fibroblast growth factor receptor (FGFR) inhibitors, such as pemigatinib, have been developed for the treatment of cholangiocarcinoma (CCA) with rearrangements or fusions in the FGFR2. FGFR inhibitors (FGFRis) have dermatologic side effects such as dry skin or nail bed damage. However, in very rare instances, a life-threatening vascular calcification disease known as calciphylaxis has been linked to these therapies.
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- The incidence of End Stage Renal Disease (ESRD) is notably higher in men, prompting an investigation into gender-specific gene expression in both healthy and diseased kidneys.
- A study analyzed 42 human kidney samples and identified distinct gender-biased genes, revealing that the majority of these genes varied between healthy and diseased conditions.
- Results indicate that men and women experience different kidney responses to injury, which could lead to tailored treatment strategies for kidney disease based on gender.