Lamin A is an intermediate filament protein which is cleaved by the enzyme, FACE 1 at VTRSY↓L. The cleavage is the final step in the production of the mature lamin A protein. The mature lamin A protein localizes in the inner membrane of the nucleus.
View Article and Find Full Text PDFLamin A is an intermediate filament protein found in most of the differentiated vertebrate cells but absent in stem cells. It shapes the skeletal frame structure beneath the inner nuclear membrane of the cell nucleus. As there are few studies of the expression of lamin A in invertebrates, in the present work, we have analyzed the sequence, immunochemical conservation and expression pattern of lamin A protein in the earthworm Eudrilus eugeniae, a model organism for tissue regeneration.
View Article and Find Full Text PDFThe earthworm, Eudrilus eugeniae, has a prodigious ability to regenerate lost segments. The skin of the worm has an outermost epidermal layer followed by a thick circular muscle layer and an innermost thin longitudinal cell layer. During the process of regeneration, the circular muscle layer decreased in thickness, and longitudinal cell layer increased.
View Article and Find Full Text PDF