High faecal calprotectin levels in intestinal tuberculosis are associated with granulomas in intestinal biopsies.

Background: The diagnosis of intestinal tuberculosis (ITB) is sometimes difficult to establish and requires endoscopic investigation with biopsies for histopathological examination. This study aimed to evaluate calprotectin as a marker of inflammation in ITB.

Methods: Patients with ITB were prospectively recruited in Southern India from October 2009 until July 2012.

Faecal calprotectin levels differentiate intestinal from pulmonary tuberculosis: An observational study from Southern India.

Background: Current methods to establish the diagnosis of intestinal tuberculosis are inadequate.

Objectives: We aimed to determine the clinical features of intestinal tuberculosis and evaluate inflammatory biomarkers in intestinal as well as pulmonary tuberculosis.

Methods: We recruited 38 intestinal tuberculosis patients, 119 pulmonary tuberculosis patients and 91 controls with functional gastrointestinal disorders between October 2009 and July 2012 for the investigation of clinical features, C-reactive protein (CRP), faecal and serum calprotectin.

Routine diagnosis of intestinal tuberculosis and Crohn's disease in Southern India.

Aim: To investigate whether routinely measured clinical variables could aid in differentiating intestinal tuberculosis (ITB) from Crohn's disease (CD).

Methods: ITB and CD patients were prospectively included at four South Indian medical centres from October 2009 to July 2012. Routine investigations included case history, physical examination, blood biochemistry, ileocolonoscopy and histopathological examination of biopsies.