Publications by authors named "Ramakrishnan M"

The global population growth is driving up the demand for agricultural products, while traditional farming methods like those from the Green Revolution are becoming unsustainable due to climate change. To address these challenges and ensure agricultural sustainability, innovative techniques, such as nanotechnology, are essential to meet rising food demands and enhance agricultural sustainability. Nanotechnology, which promotes a more sustainable and resilient agricultural system while enhancing food security, is a key catalyst for the Agri-tech revolution.

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Global initiatives aim to curb tuberculosis (TB) by developing efficient vaccines and drugs against Mycobacterium tuberculosis (M. tb). The pressing need for innovative and swift anti-TB drug screening methods, due to the drawbacks of traditional approaches, is met by employing Structure-based virtual screening (SBVS) and machine learning (ML) in drug discovery.

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  • Cervical carcinoma is the second most common cancer among women globally, with Indian women over 15 years old being particularly at risk, influenced by factors like diabetes, smoking, and contraceptives.
  • The study compared cervical cancer patients with and without diabetes across different menopausal stages, utilizing data analysis software for statistical significance.
  • Results indicated that post-menopausal women with diabetes are at a heightened risk for cervical cancer, suggesting the need for regular screening in this population and highlighting the need for further research.
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Neuroinflammation in response to environmental stressors is an important common pathway in a number of neurological and psychiatric disorders. Responses to immune-mediated stress can lead to epigenetic changes and the development of neuropsychiatric disorders. Isothiocyanates (ITC) have shown promise in combating oxidative stress and inflammation in the nervous system as well as organ systems.

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  • Perceived social support plays a crucial role in predicting the severity of PTSD and complex PTSD symptoms after experiencing trauma, but gender differences in responses to this support have not been extensively studied.
  • In a study involving 2,483 adults across 39 countries, it was found that females reported higher PTSD and complex PTSD symptoms compared to males, while no significant gender differences in perceived social support were observed.
  • Both male and female participants with low perceived social support experienced greater PTSD and complex PTSD symptoms, with some evidence suggesting that the relationship between perceived social support and PTSD symptoms might be stronger for males.
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Background: Leaf senescence (LS), the final phase in leaf development, is an important and precisely regulated process crucial for plant well-being and the redistribution of nutrients. It is intricately controlled by various regulatory factors, including WRKY transcription factors (TFs). WRKYs are one of the most significant plant TF families, and several of them are differentially regulated and important during LS.

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Evidence shows that obstructive sleep apnea (OSA) is associated with the development of stroke. This study investigates the relationship between OSA and post-stroke complications, addressing the limited data on how OSA influences the severity and development of these complications through a systematic review of existing literature. Data was collected from PubMed, Web of Science, and Scopus databases up to December 2023.

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  • Performing pattern recognition in the optical domain can offer benefits like high-speed operation and the ability to adjust and scale based on optical wave properties.
  • This study combines optical correlation with optical biasing to achieve efficient QPSK pattern recognition using direct detection, eliminating the need for complex coherent detection.
  • The experimental results show successful error-free recognition of multiple QPSK patterns over 3072 symbols at different baud rates, indicating effective performance with specific power thresholding values.
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Compared to its electronic counterpart, optically performed matrix convolution can accommodate phase-encoded data at high rates while avoiding optical-to-electronic-to-optical (OEO) conversions. We experimentally demonstrate a reconfigurable matrix convolution of quadrature phase-shift keying (QPSK)-encoded input data. The two-dimensional (2-D) input data is serialized, and its time-shifted replicas are generated.

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Childhood maltreatment (CM) is thought to be associated with altered responses to social stimuli and interpersonal signals. However, limited evidence exists that CM is linked to larger comfortable interpersonal distance (CID) - the physical distance humans prefer towards others during social interactions. However, no previous study has investigated this association in a comprehensive sample, yielding sufficient statistical power.

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Withanolides are naturally occurring steroidal lactones found in certain species of the genus, especially (commonly known as Ashwagandha). These compounds have gained considerable attention due to their wide range of therapeutic properties and potential applications in modern medicine. To meet the rapidly growing demand for withanolides, innovative approaches such as in vitro culture techniques and synthetic biology offer promising solutions.

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In this paper, we experimentally demonstrate an 8-Gbit/s quadrature-phase-shift-keying (QPSK) coherent underwater wireless optical communication (UWOC) link under scattering conditions at 532 nm. At the transmitter, we generate the 532-nm QPSK signal using second-harmonic generation (SHG), where the 1064-nm signal modulated with four phase levels of an 8-phase-shift-keying (8-PSK) format is phase doubled to produce the 532-nm QPSK signal. To enhance the receiver sensitivity, we utilize a local oscillator (LO) at the receiver from an independent laser source.

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Pediatric endodontics in the primary teeth is chemomechanical due to the difficulties encountered in cleaning and shaping the root canals having complex anatomical configurations. Not only are obturating materials having ideal properties to be used in the primary teeth, but also imparting an impervious hermetic seal to prevent the nidus of reinfection is highly pivotal for the success of pulpectomy. However, certain obturating materials contain one or the other components that are irritant to the periapical region and aggravates the inflammatory process.

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Approximately 30% of milk protein is β-casein. We aimed to determine whether lactose maldigesters who chronically consumed two cups of A1/A2 milk (containing 75% A1 β-casein and 25% A2 β-casein) would adapt to have fewer intolerance symptoms, lower serum inflammatory markers, and/or altered glutathione levels similar to those consuming A2 milk (containing 100% A2 β-casein). A double-blinded, randomized, crossover trial was conducted.

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  • The study explored the morphological variations of 16 Moso bamboo populations, highlighting significant discrepancies in culm heights, internode numbers, and dimensions across these populations.
  • It found strong positive correlations among culm parameters like diameter, thickness, and volume, which all influence overall culm height and structure.
  • Additionally, the analysis uncovered a notable negative correlation between precipitation and internode characteristics, particularly during winter months, suggesting that weather patterns affect bamboo growth.
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Advancements in retinal imaging have augmented our understanding of the pathology and structure-function relationships of retinal disease. No single diagnostic test is sufficient; rather, diagnostic and management strategies increasingly involve the synthesis of multiple imaging modalities. This literature review and editorial offer practical clinical guidelines for how the retina specialist can use multimodal imaging to manage retinal conditions.

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The K uptake permease/high-affinity K/K transporter (KUP/HAK/KT) family is the most prominent group of potassium (K) transporters, playing a key role in K uptake, transport, plant growth and development, and stress tolerance. However, the presence and functions of the KUP/HAK/KT family in Moso bamboo ( (Carriere) J. Houzeau), the fastest-growing plant, have not been studied.

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Background: KNOTTED1-like homeobox (KNOX) genes, plant-specific homologous box transcription factors (TFs), play a central role in regulating plant growth, development, organ formation, and response to biotic and abiotic stresses. However, a comprehensive genome-wide identification of the KNOX genes in Moso bamboo (Phyllostachys edulis), the fastest growing plant, has not yet been conducted, and the specific biological functions of this family remain unknown.

Results: The expression profiles of 24 KNOX genes, divided into two subfamilies, were determined by integrating Moso bamboo genome and its transcriptional data.

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The availability of big data can transform the studies in biomedical research to generate greater scientific insights if expert labeling is available to facilitate supervised learning. However, data annotation can be labor-intensive and cost-prohibitive if pixel-level precision is required. Weakly supervised semantic segmentation (WSSS) with image-level labeling has emerged as a promising solution in medical imaging.

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-methyladenosine (mA) in eukaryotes is the most common and widespread internal modification in mRNA. The modification regulates mRNA stability, translation efficiency, and splicing, thereby fine-tuning gene regulation. In plants, mA is dynamic and critical for various growth stages, embryonic development, morphogenesis, flowering, stress response, crop yield, and biomass.

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Moso bamboo typically grows in phosphorus (P)-deficient soil that limits its growth and development. In this study, 10 Moso bamboo genotypes (Ph-1 to Ph-10) were evaluated for their responses to P deficiency during the seedling stage by growing them in both P-sufficient and P-deficient conditions. Adaptive responses to low P (LP) conditions were observed in the majority of genotypes.

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